Protein A Resins Market Size By Application (Immunoprecipitation, Antibody Purification), By Product (Natural protein A, Recombinant Protein A), By Matrix (Agarose, Glass/Silica Gel, Organic Polymer), By End Use (Biopharmaceutical, Clinical Research, Academic Research, CRO), Industry Analysis Report, Regional Outlook (U.S., Canada, Germany, UK, Spain, Italy, Russia, Poland, Japan, China, India, Australia, Argentina, Brazil, Mexico, South Africa, UAE, Saudi Arabia, Qatar, Kuwait, Egypt), Growth Potential, Price Trends, Competitive Market Share & Forecast, 2016 – 2024
Published Date: January 2017 | 127 Pages | Report ID: GMI1146 Report Format: PDF
Protein A Resins Market size was more than USD 440 million in 2015, expected to grow at over 8.4% CAGR from 2016 to 2024.
Japan Protein A Resin Market size, by matrix type, 2012-2024 (USD Million)
Growing use of monoclonal antibodies in management of chronic diseases such as cancer, rheumatoid arthritis along with increasing R&D activities on monoclonal antibodies will drive protein A resins market size over the forecast period. Rising demand for biosimilars and increasing investments for development of efficacious biosimilar alternative will fuel industry growth.
Technology innovation in protein purification process and protein separation techniques such as chromatography, filtration, precipitation will assure extraction of pure quality protein. Availability of effective purification technology will increase demand for biosimilar products and monoclonal antibodies, propelling protein A resins market growth.
Favourable regulatory scenario for biosimilar development and effective harmonization of approval and registration guidelines in some of the major markets will accelerate protein A resins market growth. Growing number of industry participants are focusing on development of biosimilars to reduce the soaring drug development cost.
Protein A Resins Market, By Product
Natural protein A resin will growth at over 8% from 2016 to 2024 with expectations to exceed USD 580 million by 2024. Some of its features such as increased antibody yield, excellent antibody purification, ease of operation, and high antibody selectivity will stimulate segment growth.
Recombinant protein A resins accounted for more than 35% of the revenue share in 2015, with expectations to grow at 8.3% from 2016 to 2024. This segment will lose its market share to natural protein A resins due its sensitivity to alkaline conditions. High cost of protein A resins and growing awareness regarding availability of alternative methods for purification of monoclonal antibodies will hinder growth.
Protein A Resin Market, By Application
Antibody purification drives the protein A resins market size, with expectations to surpass USD 700 million by 2024. Growing demand for novel antibodies for diagnostics and treatment of chronic disorders such as cancer, should boost business growth.
Immunoprecipitation accounted for more than 20% of protein A resins market share in 2015, witnessing a growth of over 8% from 2016 to 2024. Increasing applications of immunoprecipitation in purification of specific compounds from the mixtures will drive industry expansion over the forecast period.
Protein A Resins Market, By Matrix
Agarose-based matrix will account for over 80% of protein A resins market share in 2015 and is expected to witness 8.3% CAGR from 2016-2024. Higher specificity and ligand binding stability of agarose-based protein A resin will drive industry growth over the forecast years.
Glass or Silica gel-based matrix will manifest a healthy 8.4% growth from 2016-2024. These matrices types have limited applications as they require rigid matrices of glass and organic polymers with good flow properties.
Protein A Resins Market, By End Use
Biopharmaceutical companies accounted for over 75% of protein A resins market share in 2015, with target market size anticipated to exceed USD 680 million by 2024. Growing demand for monoclonal and recombinant antibodies produced for therapeutic and diagnostics applications in biopharmaceutical companies will drive the industry growth.
Contract research organizations (CROs) will grow at over 8.1% from 2016 to 2024 with estimated market size slated to exceed USD 130 million by 2024. Large-scale protein production services will enable pharmaceutical & biotechnology companies, as well as academic institutions to outsource their protein purification processes to CROs.
Protein A Resins Market, By Region
U.S. Protein A resins market size accounted for more than 85% of regional revenue in 2015. Increasing use of monoclonal antibodies, favorable regulatory environment and growing number of industry participants driving development of biosimilars will promote business growth.
Japan protein A resins market share was more than USD 37 million in 2015, and anticipated to surpass USD 78 million by 2024. Growing demand for monoclonal antibodies and presence of stringent government regulations will stimulate industry growth.
Mexico protein A resins market is projected to witness 8% growth from 2016 to 2024. Increasing applications of monoclonal antibodies in clinical research will spur industry growth. However, lack of infrastructure for purification of antibodies should restrain rapid industry expansion over the forecast period.
Competitive Market Share
Companies operating in protein A resins market comprise of GE Healthcare, Repligen, Tosoh Bioscience, Thermo Fisher Scientific, GenScript, Merck Millipore (EMD Millipore), Novasep, Expedeon, Bio-Rad Laboratories, Danaher Corporation, Sigma-Aldrich, Purolite Life Sciences, Takara Bio and Agarose Bead Technologies.
Increased focus on expanding market share by strategic collaborations, along with development of existing product portfolio in research and life science catalogues remains a key business strategy for GenScript and Novasep.
Protein A Resins Industry Background
Companies operating in the industry are enormously investing in research and development processes to gain competitive advantage and offer distinguished solutions. Technological advancements and innovation will continue to be key industry drivers for next few years. Geographic expansion, agreements, strategic acquisitions, and new product development are some of the major strategies adopted by key industry participants.
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