Download free PDF

Protein Engineering Market Size & Share 2024 – 2032

Market Size by Product (Instrument, Reagent, Software & Services), Technology (Irrational, Rational), Protein (Insulin, Monoclonal Antibody, Vaccine, Growth Factor, Coagulation Factor, Interferon), End Use – Global Forecast.

Report ID: GMI8008
   |
Published Date: February 2024
 | 
Report Format: PDF

Download Free PDF

Protein Engineering Market Size

Protein Engineering Market size was valued at over USD 2.5 billion in 2023 and is estimated to grow at 15.9% CAGR from 2024 to 2032 due to the growing collaborations and partnerships for fostering innovations and advancements in the field.

Protein Engineering Market Key Takeaways

Market Size & Growth

  • 2023 Market Size: USD 2.5 Billion
  • 2032 Forecast Market Size: USD 9.3 Billion
  • CAGR (2024–2032): 15.9%

Key Market Drivers

  • Rising prevalence of protein-deficient diseases.
  • Increase in adoption of protein drugs over non-protein drugs.
  • Increasing research & development activities in the biopharmaceutical industry.
  • Growing funding opportunities for protein engineering.

Challenges

  • High costs of protein engineering techniques.
  • Limited availability of qualified researchers.

Researchers and biotech firms are pooling resources and expertise to develop novel techniques for protein modification and designs. This ongoing synergy among industry stakeholders is promising to transform drug discovery and biotechnology leading to the creation of new therapeutics and diagnostics with improved efficacy and specificity for benefiting patients worldwide. For instance, in March 2024, BRAIN Biotech and AMSilk collaborated on protein engineering for enhancing structural proteins for performance materials. This partnership marked the first patent application, showcasing BRAIN Biotech's reliance on protein engineering and bioinformatics for rational protein design.
 

The rising frequency of protein-deficient disorders, such as marasmus and kwashiorkor especially in developing and underdeveloped countries, is also increasing the demand for protein engineering. Scientists are continually developing novel protein-based therapies to combat these conditions while focusing to provide effective treatment options for the affected population.
 

Furthermore, protein engineering will play an increasingly pivotal role in addressing protein-deficient disorders by creating enhanced therapeutic proteins with improved efficacy and accessibility. The ongoing research for focusing on developing cost-effective solutions to ensure that these vital treatments reach those in need across the globe will also favor the industry development. For instance, in May 2023, UNICEF highlighted that nearly half of the deaths in children under 5 years of age stem from undernutrition. This is underscoring the critical role of protein engineering in developing nutritional interventions to combat undernutrition for potentially reducing mortality rates and enhancing child health globally.
 

However, the high development costs and limited clinical validation may hinder the market progress to some extent. Researchers are seeking innovative funding models and conducting ongoing trials to address these challenges. In addition, collaborations between academia, industry, and regulatory bodies will play a vital role in reducing costs and enhancing validation processes, ultimately facilitating the translation of protein engineering research into clinical applications.
 

Protein Engineering Market

Protein Engineering Market Trends

The increasing number of government initiatives is driving technological advancements. Governments are actively funding R&D projects for tackling protein-deficient disorders. Scientists are collaborating with policymakers to create innovative protein-based therapies and preventive measures. Moreover, government support will continue to propel the market growth for fostering the creation of more effective and accessible treatments for malnutrition-related diseases. This concerted effort will underscore the commitment to improving global health outcomes and addressing the root causes of protein deficiency.

For instance, the Japanese government's AI research initiative is boosting advancements in biopharmaceuticals, such as RevolKa, a biotech start-up that leverages machine learning to expedite protein engineering.
 

Protein Engineering Market Analysis

Protein Engineering Market, By Product, 2021 – 2032 (USD Billion)

Based on product, the reagents segment may exhibit 16.2% CAGR through 2032. Reagents play a crucial role in protein engineering, with researchers continuously refining and developing new ones. These substances enable the manipulation and modification of proteins for various applications from drug development to biotechnology. Subsequently, advancements in reagent technology will further enhance the precision and efficiency of protein engineering processes, further opening new possibilities for therapeutic interventions and scientific discoveries in fields, such as personalized medicine and biomaterials engineering.
 

Protein Engineering Market, By Technology (2023)

In terms of technology, the protein engineering market size from the rational protein design segment is expected to reach over USD 6.15 billion by 2032. This expansion is due to the growing prominence of rational protein design as a cornerstone of protein engineering, with scientists applying computational methods to predict and optimize protein structures and functions. This approach is allowing the creation of novel proteins with desired properties for specific applications, such as drug development and biocatalysis.
 

Moreover, ongoing advancements in computational algorithms and molecular modeling techniques will continue to refine rational protein design for enabling the generation of tailor-made proteins with enhanced performance and functionality, thus driving innovation in diverse fields ranging from medicine to materials science.
 

On the basis of protein type, the protein engineering market from the monoclonal antibodies segment is poised for significant growth at 16% CAGR through 2032. Scientists are engineering monoclonal antibodies for targeted therapies, diagnostics, and vaccine development for expanding their applications in treating various diseases, such as cancer and autoimmune disorders. Additionally, continuous refinement of monoclonal antibody design and production techniques will enhance their specificity, potency, and safety profiles. This ongoing innovation will pave the way for more effective and personalized treatments while heralding a new era in precision medicine where monoclonal antibodies play a pivotal role in improving patient outcomes.
 

Based on end-use, the market value from the pharmaceutical & biotechnology segment is predicted to record over USD 4.19 billion by 2032. This is due to the rising protein engineering advancements in pharmaceuticals and biotechnology for continuously improving drug development and biotech applications. Scientists are manipulating protein structures for  enhancing their functions and designing novel molecules for therapeutic purposes. Researchers are also employing cutting-edge technologies to engineer proteins with unprecedented precision for opening new avenues for tackling diseases and improving human health.
 

North America Protein Engineering Market, 2020 – 2032 (USD Million)

North America protein engineering market is predicted to record more than USD 3.75 billion by 2032 due to the notable shift towards sustainable and green technologies in the region. Companies are investing in R&D to develop eco-friendly processes for protein engineering. Additionally, there is a rising focus on personalized medicine as healthcare providers are increasingly tailoring treatments to individual patients based on genetic makeup and other factors. Multiple regional firms are also increasingly integrating sustainable practices into protein engineering processes and advancing personalized medicine approaches to provide more targeted and effective treatments for patients.
 

Protein Engineering Market Share

These industry players are developing innovative technologies as well as products and are continuously investing in R&D and expanding their portfolios to meet the evolving market demands. They are also indulging in partnership ventures to widen their global presence and customer base.
 

Protein Engineering Market Companies

Some of the major protein engineering industry players are:

  • Agilent Technologies, Inc.
  • Amgen Inc.
  • Bio-Rad Laboratories, Inc.
  • Bristol Myers Squibb Company
  • Bruker Corporation
  • Danaher Corporation
  • Genentech, Inc.
  • Integrated DNA Technologies, Inc.
  • Lonza Group
  • Merck KGaA
  • Thermo Fisher Scientific Inc.
  • Vertex Pharmaceuticals Incorporated
     

Protein Engineering Industry News

  • In April 2023, Adaptyv Biosystems inaugurated a protein engineering foundry for introducing innovative tools for swift and cost-effective validation of AI-designed proteins.
     
  • In July 2022, Amgen partnered with Generate Biomedicines to discover and advance protein therapies for five clinical targets across diverse therapeutic areas. The collaboration included a USD 50 million upfront payment for positioning Amgen competitively.
     

Protein engineering market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2018 to 2032 for the following segments:

Market, By Product

  • Instruments
  • Reagents
  • Software & services

Market, By Technology

  • Irrational protein design
  • Rational protein design

Market, By Protein Type

  • Insulin
  • Monoclonal antibodies
  • Vaccines
  • Growth factors
  • Coagulation factors
  • Interferon
  • Other protein types

Market, By End-use

  • Academic research institutes
  • Contract research organizations (CROs)
  • Pharmaceutical & biotechnology companies

The above information is provided for the following regions and countries:

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Argentina
    • Rest of Latin America
  • Middle East and Africa
    • South Africa
    • Saudi Arabia
    • UAE
    • Rest of Middle East and Africa

 

Authors:  Mariam Faizullabhoy, Gauri Wani

Research methodology, data sources & validation process

This report draws on a structured research process built around direct industry conversations, proprietary modelling, and rigorous cross-validation and not just desk research.

Our 6-step research process

  1. 1. Research design & analyst oversight

    At GMI, our research methodology is built on a foundation of human expertise, rigorous validation, and complete transparency. Every insight, trend analysis, and forecast in our reports is developed by experienced analysts who understand the nuances of your market.

    Our approach integrates extensive primary research through direct engagement with industry participants and experts, complemented by comprehensive secondary research from verified global sources. We apply quantified impact analysis to deliver dependable forecasts, while maintaining complete traceability from original data sources to final insights.

  2. 2. Primary research

    Primary research forms the backbone of our methodology, contributing nearly 80% to overall insights. It involves direct engagement with industry participants to ensure accuracy and depth in analysis. Our structured interview program covers regional and global markets, with inputs from C-suite executives, directors, and subject matter experts. These interactions provide strategic, operational, and technical perspectives, enabling well-rounded insights and reliable market forecasts.

  3. 3. Data mining & market analysis

    Data mining is a key part of our research process, contributing nearly 20% to the overall methodology. It involves analysing market structure, identifying industry trends, and assessing macroeconomic factors through revenue share analysis of major players. Relevant data is collected from both paid and unpaid sources to build a reliable database. This information is then integrated to support primary research and market sizing, with validation from key stakeholders such as distributors, manufacturers, and associations.

  4. 4. Market sizing

    Our market sizing is built on a bottom-up approach, starting with company revenue data gathered directly through primary interviews, alongside production volume figures from manufacturers and installation or deployment statistics. These inputs are then pieced together across regional markets to arrive at a global estimate that stays grounded in actual industry activity.

  5. 5. Forecast model & key assumptions

    Every forecast includes explicit documentation of:

    • ✓ Key growth drivers and their assumed impact

    • ✓ Restraining factors and mitigation scenarios

    • ✓ Regulatory assumptions and policy change risk

    • ✓ Technology adoption curve parameter

    • ✓ Macroeconomic assumptions (GDP growth, inflation, currency)

    • ✓ Competitive dynamics and market entry/exit expectations

  6. 6. Validation & quality assurance

    The final stages involve human validation, where domain experts manually review filtered data to identify nuances and contextual errors that automated systems might miss. This expert review adds a critical layer of quality assurance, ensuring data aligns with research objectives and domain-specific standards.

    Our triple-layer validation process ensures maximum data reliability:

    • ✓ Statistical Validation

    • ✓ Expert Validation

    • ✓ Market Reality Check

Trust & credibility

10+
Years in Service
Consistent delivery since establishment
A+
BBB Accreditation
Professional standards & satisfaction
ISO
Certified Quality
ISO 9001-2015 Certified Company
150+
Research Analysts
Across 10+ industry verticals
95%
Client Retention
5-year relationship value

Verified data sources

  • Trade publications

    Security & defense sector journals and trade press

  • Industry databases

    Proprietary and third-party market databases

  • Regulatory filings

    Government procurement records and policy documents

  • Academic research

    University studies and specialist institution reports

  • Company reports

    Annual reports, investor presentations, and filings

  • Expert interviews

    C-suite, procurement leads, and technical specialists

  • GMI archive

    13,000+ published studies across 30+ industry verticals

  • Trade data

    Import/export volumes, HS codes, and customs records

Parameters studied & evaluated

Every data point in this report is validated through primary interviews, true bottom-up modelling, and rigorous cross-checks. Read about our research process →

Frequently Asked Question(FAQ) :
How big is the protein engineering industry?
Protein engineering market size was over USD 2.5 billion in 2023 and is expected to register 15.9% CAGR from 2024-2032 owing to the growing collaborations and partnerships for fostering innovations and advancements in the field, worldwide.
Why is the use of reagents in protein engineering growing?
Protein engineering industry from the reagents segment is expected to register 16.2% CAGR from 2024-2032 due to playing a crucial role in protein engineering, with researchers continuously refining and developing new ones.
What is the size of the North America protein engineering market?
North America protein engineering industry is expected to reach over USD 3.75 billion by 2032 due to notable shift towards sustainable and green technologies in the region.
Who are the key leaders in the protein engineering industry?
Amgen Inc., Bruker Corporation, Danaher Corporation, Genentech, Inc., Integrated DNA Technologies, Inc., Lonza Group, Merck KGaA, Thermo Fisher Scientific Inc., and Vertex Pharmaceuticals Incorporated, are some of the major protein engineering companies worldwide.
Protein Engineering Market Scope
  • Protein Engineering Market Size

  • Protein Engineering Market Trends

  • Protein Engineering Market Analysis

  • Protein Engineering Market Share

Authors:  Mariam Faizullabhoy, Gauri Wani
Explore Our Licensing Options:

Starting at: $2,450

Premium Report Details:

Base Year: 2023

Companies Profiled: 12

Tables & Figures: 276

Countries Covered: 22

Pages: 155

Download Free PDF

We use cookies to enhance user experience. (Privacy Policy)