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Enzyme Market Size & Share 2026-2035

Report ID: GMI743
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Published Date: October 2026
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Enzyme Market Size

The enzyme market was valued at USD 14.38 billion in 2025, is estimated at USD 15.34 billion in 2026, and is projected to grow at a 6.8% CAGR (2026–2035) to reach USD 27.78 billion by 2035.

Enzyme Market Key Takeaways

2025 Market Size
$ 14.38 Billion
2026 Market Size
$ 15.34 Billion
2035 Forecast Market Size
$ 27.78 Billion
CAGR (2026–2035)
6.8%
Regional Dominance
Largest Market
North America
Fastest Growing Region
Asia Pacific
Key Players
  • Market Leader: Novonesis A/S led with over 19% market share in 2025.

  • Leading Players: Top 5 players in this market include Novonesis A/S, IFF Inc., BASF SE, Advanced Enzyme Technologies Ltd., Kerry Group plc, which collectively held a market share of 40% in 2025.

The enzyme market encompasses commercial and industrial enzyme formulations supplied to food processing, feed, biofuels, detergents, textiles, pharmaceutical manufacturing, diagnostics, and environmental applications. Demand is being reshaped by the migration of enzymes from high-volume process aids toward increasingly specified inputs in bioprocessing, precision manufacturing, and resource-efficient production.

GMI Analyst View

Based on our discussions with senior industry stakeholders, we estimate the enzyme market accounted for approximately 1,030 KMT of formulated enzyme product volume in 2025. This scale reflects the extensive fermentation, processing, formulation, and distribution infrastructure required to serve a broad mix of industrial and specialty applications.

Enzyme Market Trends, Growth Drivers & GMI Forecast Outlook

Biofuel output, food-system industrialization, and biopharmaceutical manufacturing are broadening enzyme demand beyond mature commodity uses. Growth remains dependent on the ability of producers to qualify products across jurisdictions, preserve supply continuity, and translate advances in protein engineering into commercially scalable formulations.

Key Drivers

Driver Evidence signal Market-demand implication GMI forecast condition
Biofuels & bioethanol processing expansion U.S. fuel ethanol production capacity reached nearly 18.5 billion gallons per year across 191 operating plants as of January 2025 [1] Cellulase and amylase procurement volumes scale directly with ethanol throughput at corn wet-milling and cellulosic conversion facilities Sustained U.S. capacity additions under Renewable Fuel Standard mandates maintain commercial enzyme offtake through 2035
Cross-regional structural demand growth Global enzyme trade (HS 3507) reached USD 7.63 billion in 2024 [2] Rising cross-border enzyme flows across food, animal feed, pharma, and industrial sectors signal structural multi-sector demand Geographic diversification underpins the GMI 6.8% CAGR through 2035
AI-guided enzyme engineering expanding addressable applications Directed-evolution platforms integrating machine learning with high-throughput screening enabling thermostable, process-specific variants Improved performance widens addressable industrial and specialty application scope Widening performance envelope sustains volume and revenue growth into higher-margin novel end-uses through 2035

*Evidence anchors use cited external data; demand implications and forecast conditions represent GMI analysis.*

Biofuel producers use enzymes as operating inputs rather than discretionary additives: amylases support starch conversion, while cellulase systems underpin more complex lignocellulosic pathways. High utilization at ethanol facilities can therefore create repeat procurement cycles and favor suppliers that can provide stable activity, formulation consistency, and technical service at plant scale.

Cross-border trade also signals that enzyme demand is broadening across food, feed, pharmaceutical, and industrial value chains rather than relying on one end market. As processors in developing manufacturing centers adopt more standardized production methods, enzyme suppliers gain access to a wider customer base, although local technical support and registration capabilities remain essential to converting demand into recurring sales.

Protein engineering is expanding the practical operating envelope for enzyme products. Improved temperature tolerance, substrate specificity, and compatibility with demanding process conditions can make enzymatic routes viable where conventional catalysts, high-temperature processing, or chemical inputs have historically prevailed.

Key Restraints

Restraint Evidence signal Market-demand implication GMI forecast condition
Geographic supply concentration risk Denmark alone accounted for USD 1.79 billion of global enzyme exports (HS 3507) in 2024 [2] Industrial buyers in Asia Pacific, Latin America, and MEA face elevated procurement risk Supply concentration moderates regional market expansion, particularly through 2030
Trade-growth lag vs. market expansion Global enzyme trade grew 4.9% from 2023 to 2024 [2] Trade friction and import-substitution in China and India raise landed costs and compress margins Persistent lag moderates net revenue growth for globally oriented formulators
Multi-jurisdictional regulatory authorization complexity EU Positive List of Food Enzymes targets finalization by 2028 [3]; parallel U.S. GRAS and China frameworks add burden Mid-sized producers face delayed market entry, concentrating viability among larger incumbents EU authorization timelines moderate European market entry for niche food enzyme categories through 2028

*Evidence anchors use cited external data; demand implications and forecast conditions represent GMI analysis.*

Supply concentration creates a particular challenge for buyers of specialized or pharmaceutical-grade products, where changing suppliers requires technical validation, quality review, and often renewed regulatory work. Import-dependent markets may consequently face longer replenishment cycles and greater exposure to logistics disruption than locally supplied commodity categories.

A slower rise in recorded trade than in broader demand also reflects growing local production and import-substitution efforts. This can improve supply security for domestic customers, but it places pressure on export-oriented formulators whose differentiated value proposition must justify higher landed costs.

Regulatory pathways remain commercially consequential because food and specialty enzymes are not universally portable across markets. Producers with established toxicology, dossier-preparation, and application-support capabilities are better positioned to manage approval timelines, whereas smaller firms can face delayed entry even where technical performance is competitive.

GMI Analyst View

We view the market's central tension as a shift toward higher-value enzyme applications occurring alongside increasingly localized supply strategies. Suppliers that pair differentiated performance with regulatory and application expertise should capture more durable opportunities than those competing principally on fermentation scale or unit cost.

Enzyme Market Segment Analysis

By Enzyme Type

Carbohydrases accounted for 35.0% of the enzyme market in 2025 and are projected to generate USD 9.32 billion by 2035. Amylases, cellulases, xylanases, and related products retain broad relevance in starch conversion, baking, beverage processing, animal nutrition, and biofuels. Their diversity of end uses helps offset exposure to individual downstream cycles, while large-scale fermentation continues to support competitive supply economics.

Global Enzyme Market Size, by Enzyme Type, 2025 & 2035 (USD Million)
Global Enzyme Market Size, by Enzyme Type, 2025 & 2035 (USD Million)

Proteases generated USD 3.60 billion in 2025 and are projected to hold a 24.7% share of the market by 2035. Detergent formulations remain an important volume base for alkaline proteases, while food processing, wound care, and bioprocessing favor products with more narrowly defined substrate performance. This combination supports both commodity demand and selective movement into higher-specification contracts.

Lipases held a 12.0% share of the market in 2025 and are forecast to grow at a 7.3% CAGR (2026–2035). Lipase demand is supported by food processing, oleochemicals, and specialty synthesis, where lower-temperature enzymatic processing can improve selectivity and reduce process intensity. Commercial adoption depends on whether customers can validate enzyme performance within existing capital equipment and operating protocols.

Polymerases & nucleases generated USD 1.15 billion in 2025 and are expected to account for 10.1% of the market by 2035. This category is closely tied to molecular diagnostics, sequencing, RNA therapeutics, and advanced biomanufacturing. Qualification standards, purity requirements, and supply assurance create meaningful barriers to entry and can strengthen supplier relationships once a reagent becomes embedded in a regulated workflow.

Phytases represented 7.0% of market revenue in 2025 and are projected to reach USD 2.00 billion by 2035. Feed producers use phytases to improve phosphorus availability from plant-based ingredients and to reduce dependence on supplemental inorganic phosphorus. Their adoption is reinforced by the economic importance of feed conversion and the environmental value of reducing nutrient discharge.

Others generated USD 1.87 billion in 2025 and are forecast to expand at a 5.9% CAGR (2026–2035). This group includes enzymes serving specialized functions in food texture modification, dairy processing, textiles, and environmental applications. Demand is less standardized across the category, making technical fit, local formulation expertise, and customer-specific development important commercial differentiators.

By Product Category

Industrial enzymes generated USD 7.62 billion in 2025 and are expected to hold a 51.5% share of the market by 2035. High-volume applications in detergents, starch processing, textiles, pulp and paper, and biofuels underpin this category. Competitive advantage depends heavily on fermentation efficiency, formulation reliability, distribution reach, and the ability to provide process support at scale.

Global Enzyme Market Share, by Product Category, 2025
Global Enzyme Market Share, by Product Category, 2025

Specialty enzymes accounted for 47.0% of the market in 2025 and are projected to generate USD 13.47 billion by 2035. Specialty products are increasingly linked to pharmaceutical manufacturing, molecular biology, diagnostics, and performance-sensitive food applications. These uses favor suppliers able to meet strict quality specifications, offer differentiated activity profiles, and support lengthy customer qualification programs.

By Source

Microorganism-derived enzymes accounted for 72.0% of the market in 2025 and are projected to reach USD 20.47 billion by 2035. Microbial production remains commercially attractive because it can be scaled through controlled fermentation, modified through strain engineering, and adapted to a wide range of industrial applications. Continued development of engineered yeasts, fungi, and bacterial hosts is extending microbial platforms into more specialized products.

Plant-derived enzymes generated USD 2.59 billion in 2025 and are projected to account for 17.8% of the market by 2035. Plant-origin products retain value in selected food, nutraceutical, and therapeutic uses where natural-origin positioning or established functional performance is commercially relevant. Their growth is moderated by competition from recombinant equivalents that can offer more uniform activity and dependable supply.

Animal-derived enzymes represented 10.0% of the market in 2025 and are forecast to grow at a 5.2% CAGR (2026–2035). Demand remains concentrated in products where biological specificity, clinical familiarity, or traditional food-processing functionality is difficult to replace. However, recombinant microbial alternatives are steadily narrowing the addressable space in categories where animal-free sourcing, supply consistency, or certification requirements matter.

By Form

Liquid formulations accounted for 53.0% of the market in 2025 and are projected to generate USD 14.29 billion by 2035. Liquid products suit continuous processing environments that require accurate metering and rapid incorporation into existing manufacturing systems. Their use is most attractive where refrigerated storage and handling infrastructure are available, particularly in large food, starch, textile, and beverage operations.

Powder formulations generated USD 4.60 billion in 2025 and are expected to hold a 32.6% market share by 2035. Powdered enzymes align well with dry-blending processes in feed, baking, nutraceutical, and detergent applications. Improvements in encapsulation and handling technologies are also increasing their suitability for automated production systems while reducing operational concerns related to dust and product stability.

Granules represented 15.0% of the market in 2025 and are forecast to grow at a 7.5% CAGR (2026–2035). Granular products are favored where controlled release, reduced dust, and improved formulation stability are required. Their commercial role is expanding in detergent and feed applications, where manufacturers seek safer handling and better retention of enzyme activity through downstream processing.

By Application

Food & beverage applications generated USD 4.17 billion in 2025 and are projected to account for 27.9% of the market by 2035. The enzyme market benefits from the broad use of amylases, proteases, lipases, and pectinases in bakery, dairy, brewing, starch conversion, and beverage clarification. Enzymes can improve process consistency and product attributes while helping manufacturers respond to clean-label, efficiency, and shelf-life requirements.

Animal feed accounted for 14.0% of the market in 2025 and is forecast to grow at a 7.3% CAGR (2026–2035). Feed enzymes improve nutrient utilization in poultry, swine, and aquaculture diets, linking demand to the industrialization of animal protein production. Their value proposition is strongest where formulation economics, feed-conversion performance, and nutrient-management requirements converge.

Biofuels & bioethanol represented 11.0% of the market in 2025 and are projected to generate USD 3.36 billion by 2035. This application relies on enzyme systems to improve conversion efficiency across starch-based and cellulosic production pathways. Supplier opportunity is concentrated in tailored formulations that perform consistently with specific feedstocks, plant configurations, and throughput conditions.

Detergents & cleaning applications generated USD 2.01 billion in 2025 and are projected to hold a 12.9% market share by 2035. Proteases, lipases, and other enzymes support cleaning performance at lower wash temperatures and can help formulators reduce reliance on more intensive chemical inputs. Demand is closely tied to reformulation cycles, consumer performance expectations, and sustainability targets among branded household-care suppliers.

Textiles & leather accounted for 8.0% of the market in 2025 and are forecast to grow at a 5.5% CAGR (2026–2035). Enzyme use in desizing, bio-polishing, denim finishing, and leather bating offers process-control and chemical-reduction benefits. Growth is moderated by the geographic redistribution of textile manufacturing and by uneven adoption of higher-value processing practices across facilities.

Pharmaceuticals & biotechnology generated USD 1.58 billion in 2025 and are forecast to grow at an 8.9% CAGR (2026–2035). This is the market's most specification-intensive application area, encompassing reagents and process inputs for diagnostics, biologics, RNA therapeutics, and cell and gene therapy workflows. Long qualification cycles and exacting purity requirements create a favorable environment for suppliers with robust technical documentation and manufacturing controls.

Pulp & paper represented 5.0% of the market in 2025 and are projected to generate USD 1.17 billion by 2035. Xylanases and cellulases can improve bleaching, fiber modification, and process efficiency. Packaging and specialty-paper demand support selected opportunities, although structural weakness in some graphic-paper markets limits the category's broader expansion.

Wastewater treatment accounted for 4.0% of the market in 2025 and is projected to generate USD 1.18 billion by 2035. Enzyme-based treatment solutions can assist in degrading organic load and improving process performance in food, dairy, and industrial wastewater streams. Adoption depends on local effluent enforcement, plant operating economics, and the availability of technical service that can demonstrate site-specific treatment value.

GMI Analyst View

We see a widening separation between applications where enzymes are selected primarily for unit-cost efficiency and those where they are qualified for process-critical performance. The latter should become increasingly important to market value creation because switching costs, regulatory documentation, and application know-how are more consequential than volume alone.

Enzyme Market Regional Analysis

Global Enzyme Market Share, by Region, 2025 & 2035
Global Enzyme Market Share, by Region, 2025 & 2035

North America Enzyme Market Analysis

North America generated USD 4.89 billion in 2025 and is projected to account for 31.2% of the enzyme market by 2035. The region combines major food and fuel-processing demand with a deep pharmaceutical and biotechnology base. Its mature application infrastructure supports recurring enzyme use, while advanced customers continue to create demand for highly specified products and technical service.

U.S.

The U.S. generated USD 4.06 billion in 2025 and is projected to reach USD 7.19 billion by 2035. The country's ethanol, food-processing, biotechnology, and pharmaceutical sectors provide a diversified demand base. Its concentration of research, manufacturing, and regulated end users also makes the market commercially important for validating new specialty enzyme platforms.

Canada

Canada accounted for 17.0% of North American revenue in 2025 and is projected to reach USD 1.47 billion by 2035. Food processing, grain-based industries, dairy, and bioenergy are central demand channels. Regulatory alignment and close supply relationships with the United States can reduce market-access complexity for suppliers operating across North America.

Europe Enzyme Market Analysis

Europe accounted for 27.0% of the market in 2025 and is projected to generate USD 7.00 billion by 2035. The region is both a major production center and a substantial end market for food, detergent, feed, and industrial biotechnology applications. Its evolving food-enzyme authorization framework raises the value of regulatory capabilities, while broader bioeconomy policy supports the strategic relevance of biological processing solutions [4].

Germany

Germany generated USD 893 million in 2025 and is projected to account for 22.0% of European revenue by 2035. Its large food-processing, chemical, feed, and detergent industries support demand across industrial and specialty enzyme categories. The presence of established producers and technically sophisticated customers strengthens the country's role in product development and high-specification application work.

United Kingdom

The United Kingdom generated USD 738 million in 2025 and is forecast to grow at a 5.5% CAGR (2026–2035). Food processing, brewing, pharmaceuticals, and biotechnology remain the core demand drivers. Separate regulatory requirements relative to continental Europe can increase compliance work, particularly for smaller companies without dedicated market-access resources.

France

France generated USD 621 million in 2025 and is projected to reach USD 1.08 billion by 2035. Its food and beverage industries, including dairy, bakery, and wine-related processing, remain important enzyme users. Pharmaceutical and biotechnology manufacturing adds a complementary specialty-demand channel, particularly for high-purity and process-specific products.

Asia Pacific Enzyme Market Analysis

Asia Pacific generated USD 4.03 billion in 2025 and is forecast to grow at an 8.4% CAGR (2026–2035). The region is becoming both a larger consumer market and a more influential production base. Food-system modernization, animal-protein output, and domestic biopharmaceutical investment are raising consumption, while expanding local fermentation capacity is reshaping competitive conditions in commodity enzyme categories.

China

China generated USD 1.53 billion in 2025 and is forecast to grow at an 8.9% CAGR (2026–2035). Domestic food processing, feed production, and industrial biotechnology support broad demand. Chinese producers are strengthening their position in standard enzyme categories, increasing competitive pressure on imported products and creating a larger local supplier base for regional customers.

Japan

Japan generated USD 725 million in 2025 and is projected to account for 15.0% of Asia Pacific revenue by 2035. The market is characterized by high-value food fermentation, specialty processing, and pharmaceutical applications. Its demand profile favors reliable activity specifications and specialized technical support, supporting a role in premium enzyme consumption as well as precision production.

India

India accounted for 15.0% of Asia Pacific revenue in 2025 and is forecast to grow at a 10.6% CAGR (2026–2035). Expansion in food processing, animal nutrition, and domestic pharmaceutical manufacturing is widening the customer base. Indian suppliers with integrated development and production capabilities are positioned to compete where cost-effective manufacturing must be paired with credible quality and export-market support.

South Korea

South Korea generated USD 483 million in 2025 and is projected to reach USD 943 million by 2035. Food processing remains a central use case, complemented by demand from specialty chemicals and advanced manufacturing. Customers in these applications may require greater formulation precision and purity assurance than conventional commodity-processing markets.

Latin America Enzyme Market Analysis

Latin America accounted for 7.0% of the market in 2025 and is projected to generate USD 2.04 billion by 2035. Agricultural processing, bioethanol, and animal-protein production anchor regional demand. The region's reliance on imported industrial and specialty products makes distributor capability, inventory planning, and supply reliability important competitive considerations.

Brazil

Brazil generated USD 604 million in 2025 and is projected to account for 58.0% of Latin American revenue by 2035. Sugarcane bioethanol and large-scale poultry and swine production underpin a broad enzyme requirement across biofuels and feed. The country's agricultural scale provides a durable base for high-volume applications, particularly where enzymes improve conversion efficiency or feed economics.

Mexico

Mexico accounted for 25.0% of Latin American revenue in 2025 and is forecast to grow at an 8.1% CAGR (2026–2035). Food processing and livestock production are core demand drivers. Its proximity to North American supply networks supports efficient distribution, although local market development still depends on technical support tailored to processors and feed producers.

Middle East & Africa Enzyme Market Analysis

Middle East & Africa accounted for 4.0% of the market in 2025 and is projected to generate USD 1.11 billion by 2035. The region's demand is supported by food and dairy processing, detergent production, water treatment, and growing pharmaceutical activity in selected markets. Limited local production makes procurement vulnerable to international supply conditions, but also creates opportunities for suppliers with strong regional distribution networks.

Saudi Arabia

Saudi Arabia generated USD 173 million in 2025 and is projected to account for 33.0% of Middle East & Africa revenue by 2035. Industrial diversification is expanding demand for food-processing, dairy, and pharmaceutical inputs. Suppliers that can provide application support and dependable imports are well placed to participate as domestic manufacturing capacity develops.

UAE

The UAE accounted for 25.0% of Middle East & Africa revenue in 2025 and is forecast to grow at an 8.0% CAGR (2026–2035). Its role as a regional logistics and distribution hub supports enzyme availability across the Gulf and nearby markets. Food processing, pharmaceuticals, and personal-care manufacturing provide a growing base for both industrial and specialty products.

South Africa

South Africa accounted for 20.0% of Middle East & Africa revenue in 2025 and is projected to hold a 17.0% regional share by 2035. Food processing, beverage production, textiles, and industrial effluent treatment sustain domestic enzyme demand. The country remains an important regional market, although faster expansion elsewhere in the Middle East & Africa is expected to reduce its relative share.

GMI Analyst View

We expect regional competition to be defined by the coexistence of growing Asian demand and established Western strength in specialized applications. The strategic issue is not simply where volume grows fastest, but where suppliers can maintain differentiated technical, regulatory, and service capabilities as local production ecosystems mature.

Enzyme Market Share & Competitive Landscape

The enzyme market share structure is moderately concentrated: the top five producers collectively held approximately 40% of market revenue in 2025. Scale matters because leading suppliers combine fermentation capacity, application laboratories, regulatory infrastructure, and multinational distribution, while smaller firms increasingly compete through specialization in defined enzyme families, customer segments, or technology platforms.

Novonesis A/S held a 19% share of the market in 2025. Its scale across industrial enzymes, food ingredients, animal nutrition, and specialty applications gives it substantial portfolio breadth. The company's competitive position is reinforced by fermentation infrastructure, application expertise, and the ability to support customers across multiple regulatory jurisdictions.

IFF Inc. accounted for 9% of the market in 2025. IFF is particularly relevant in food and beverage applications, where enzyme products can be embedded within broader formulation, flavor, texture, and ingredient-service relationships. This model can deepen customer retention by positioning enzymes as part of an integrated product-development solution.

BASF SE held a 6% share of the market in 2025. BASF's feed-enzyme position benefits from its broader animal-nutrition presence and from established product relationships in poultry and swine markets. Integration with adjacent nutrition offerings can support bundled commercial propositions and sustained customer access.

Advanced Enzyme Technologies Ltd. is positioned as a notable specialty-focused supplier with capabilities spanning healthcare, animal nutrition, and industrial uses. Its development and production base in India provides a link between cost-efficient manufacturing and increasingly demanding international quality requirements.

Kerry Group plc participates primarily through food-ingredient and nutrition relationships, where enzymes are incorporated into broader formulation solutions. This positioning can reduce reliance on standalone enzyme pricing and tie demand to longer-term customer development programs.

AB Enzymes GmbH, Amano Enzyme Inc., Biocatalysts Ltd., Jiangsu Boli Bioproducts Co. Ltd., Fermenta Biotech Ltd., Arzeda Corp., Codexis Inc., c-LEcta GmbH, Protein Evolution Inc., and EnginZyme AB illustrate the importance of focused capabilities in baking, feed, pharmaceutical synthesis, diagnostics, computational design, circular chemistry, and advanced biocatalytic manufacturing. Competitive intensity is rising as emerging-market producers build scale in established categories and technology-led firms target specialized, higher-margin applications.

Recent Industry Developments

In November 2025, Novonesis and thyssenkrupp Uhde introduced an enzymatic fat-splitting solution using the Novonesis Lipura® Split enzyme for oleochemical production [5]. The development demonstrates how industrial lipases can move beyond conventional processing uses into capital-intensive manufacturing routes where lower-intensity operating conditions may support broader adoption.

In January 2026, EnginZyme AB and AGC Inc. announced a scalable enzymatic process for producing N1-methylpseudouridine-5'-triphosphate, an input used in mRNA vaccine and therapeutic manufacturing [6]. The announcement highlights the growing commercial relevance of multi-enzyme systems in pharmaceutical supply chains that require specialized, quality-controlled nucleotide production.

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Authors:  Kiran Puldinidi, Kunal Ahuja

Frequently Asked Questions (FAQs):

How big is the enzyme market?
The enzyme market size was estimated at USD 14.38 billion in 2025 and is expected to reach USD 15.34 billion in 2026.
What is the 2035 forecast for the enzyme market?
The market is projected to reach USD 27.78 billion by 2035, growing at a CAGR of 6.8% from 2026 to 2035.
Which region dominates the enzyme market?
North America currently holds the largest share of the enzyme market in 2025.
Which region is expected to grow the fastest in the enzyme market?
Asia Pacific is projected to be the fastest-growing region during the forecast period.
Who are the major players in enzyme market?
Some of the major players in enzyme market include Novonesis A/S, IFF Inc., BASF SE, Advanced Enzyme Technologies Ltd., Kerry Group plc.

Research methodology, data sources & validation process

This report draws on a structured research process built around direct industry conversations, proprietary modelling, and rigorous cross-validation and not just desk research.

Our 6-step research process

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Authors:  Kiran Puldinidi, Kunal Ahuja

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