Total Knee Replacement Market Size By Product (Primary Knee Replacement Systems, Revision Knee Replacement Systems, Partial Knee Replacement Systems), By Device Type (Three-compartmental Knee Implants, Bicompartmental Knee Implants, Unicompartmental Knee Implants), By Component (Femoral, Tibial, Patellar), By Implant Type (Fixed-Bearing Implants, Mobile-Bearing Implants, Medial Pivot Implants), By Design (Cruciate Retaining, Posterior Stabilized Design), By Surgery Type (Traditional Surgery Type, Technology Assisted Surgery Type) By Fixation Material (Cemented, Cementless, Hybrid), By Material (Metal-on-plastic, Ceramic-on-plastic, Ceramic-on-ceramic, Metal-on-metal), By Polyethylene Inserts (Conventional Polyethylene Inserts, Highly Cross-Linked Polyethylene Inserts, Antioxidant Polyethylene Inserts), By End-use (Hospitals, Ambulatory Surgical Centers), Industry Analysis Report, Regional Outlook, Application Potential, Competitive Market Share & Forecast, 2020– 2026

Published Date: Jan 2020  |  Report ID: GMI2804  |  Authors: Sumant Ugalmugle, Rupali Swain

Report Format: PDF   |   Pages: 850   |   Base Year: 2019

Summary Table of Contents Industry Coverage Methodology

Industry Trends

Total Knee Replacement Market size was valued over USD 9 billion in 2019 and is expected to grow at over 4.5% CAGR up to 2026. Total knee replacement is a surgical procedure to resurface a damaged knee due to arthritis. Growing trend among doctors for using robotic technologies to treat total knee arthroplasty is booming. This is owing to several advantages it possesses such as less blood loss, less pain, less muscle dissection, shorter hospital stays, faster rehabilitation and rapid improvement in range of motion.

Total Knee Replacement Market

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Advent of total knee arthroplasty was an important milestone in orthopedic surgery. Growth of total knee replacement began back in 1860 when German surgeon Themistocles Gluck, surgically implanted the first primitive hinge joints made of ivory. Knee replacement was one of the important orthopedic surgical advances of the twentieth century. In 1968, the first knee replacement was performed, since then advancements in surgical materials and techniques have greatly increased its effectiveness.

Total Knee Replacement Market Report Coverage
Report Coverage Details
Base Year: 2019 Market Size in 2019: 9,009.1 Million (USD)
Historical Data for: 2015 to 2018 Forecast Period: 2020 to 2026
Forecast Period 2020 to 2026 CAGR: 4.5% 2026 Value Projection: 12,302.5 Million (USD)
Pages: 850 Tables, Charts & Figures: 2504
Geographies covered (52): U.S., Canada, Germany, UK, France, Spain, Italy, Russia, Austria, Belgium, Czech Republic, Denmark, Estonia, Finland, Greece, Hungary, Ireland, Lithuania, Netherlands, Norway, Poland, Portugal, Romania, Slovenia, Sweden, Switzerland, Turkey, Ukraine, China, Japan, India, Australia, South Korea, Taiwan, Indonesia, Malaysia, New Zealand, Philippines, Singapore, Thailand, Brazil, Mexico, Argentina, Colombia, Peru, Chile, South Africa, Saudi Arabia, UAE, Qatar, Kuwait, Israel
Segments covered: Product, Device Type, Component, Implant Type, Design, Surgery Type, Fixation Material, Material, Polyethylene Inserts and End-use
Companies covered (13): Stryker, Zimmer Biomet, B. Braun, ConforMIS, Inc., Smith & Nephew Medacta, DePuy Synthes, Exactech, Inc., MicroPort Scientific Corporation (Wright Medical Group), Corin Group, Waldemar LINK GmbH & Co. KG, DJO Global and C2F Implants.
Growth Drivers:
  • Rising geriatric population
  • Increasing prevalence of arthritis and osteoporosis
  • Technological advancements
  • Need for personalized and patient specific implants
  • Growing infection rates contributing to rise in knee revisions
  • Growing preference for bicruciate-retaining total knee arthroplasty
  • Increasing usage of unicondylar knee procedures
Pitfalls & Challenges:
  • Rising financial burden
  • Increased number of knee implant recalls
  • High cost associated with the surgery
  • Stringent regulations

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Rising number of patients suffering from osteoporosis and growing infectious rates will boost the adoption of knee implants across the globe

Growing number of patients with osteoporosis is expected to propel the total knee replacement industry growth positively. According to the National Osteoporosis Foundation, approximately 10 million Americans are affected with osteoporosis and another 44 million have low bone density. Such high incidences of osteoporosis have placed the population at an increased risk, thereby increasing the demand for knee replacement products. Development of non-invasive surgical procedures that cause minimum pain is further expected to drive the total knee replacement market demand.

Major players operating in the industry such as Stryker and Zimmer Biomet have undertaken certain initiatives to implement improvisations in knee replacement devices, that is boosting the industry growth significantly. Furthermore, growing infection rates are contributing to rise in knee revision, that in turn is driving the market growth. In the recent years, the rate of infection in total knee arthroplasty has increased by 0.92% owing to which the number of surgeries has increased dramatically, thereby propelling the total knee replacement industry growth.

Increasing number of primary total knee replacement surgeries will spur the market growth

Global Total Knee Replacement Market Size, By Product, 2019 (USD Million)

Total Knee Replacement Market

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Based on product, the market is segmented into primary knee replacement systems, revision knee replacement systems, and partial knee replacement systems. Primary knee replacement systems witnessed a substantial growth over the historical period and the segment was valued at USD 6.1 billion in 2015 and USD 7.4 billion in 2019. Primary knee replacement systems or total knee replacement is for the long-term relief of pain and restoration of function.

Knee osteoarthritis is a common and potentially debilitating condition and hence, total knee replacement is the mainstay treatment for osteoarthritis. Also, this procedure has shown positive results in most cases. According to an article published on Lancet Journal, in 2016, the typical patient requiring knee replacement was aged around 69 years in UK.

Additionally, around 108,713 total knee replacement procedures were performed in England, Ireland, Wales, Northern, and the Isle of Man. Thus, owing to these statistics, the segmental market is expected to gain a significant traction, thereby impelling the overall total knee replacement market revenue in the upcoming years.

Decline in the surgical trauma and improved outcomes will propel the three compartmental knee implants market growth

Based on device type, the market is segmented as three compartmental knee implants, bicompartmental knee implants and unicompartmental knee implants. Three compartmental knee replacement systems also known as tricompartmental knee replacement or total knee arthroplasty is a surgical procedure indicated for severe osteoarthritis of the knee. According to the Osteoarthritis Research Society, in 2016, osteoarthritis affected around 240 million people across the globe.

The symptoms for tricompartmental osteoarthritis are swelling, knee pain, knee stiffness, weakness or buckling of the knee. Hence, owing to these symptoms, doctors recommend tricompartmental knee replacement surgery to relieve pain and restore the alignment and function of the knee. Thus, all the above-mentioned factors are contributing to the segmental growth and thereby, propelling the market positively.

Increased knee protection by replacing femoral is expected to boost the total knee replacement market growth

Based on component, the market is segmented into femoral, tibial and patellar. Femoral emerged as the largest segment in terms of component and was valued at USD 4.5 billion in 2019. Femoral segment due to its growing demand has been witnessing a significant growth from 2015 to 2019. The growing segment is owing to the availability of superior quality of femoral component and increasing performance of surgical procedures.

Additionally, growing number of femur shaft fractures due to critical injuries caused during road accidents will propel the industry growth significantly. Thus, all these factors will positively contribute to segmental growth in the upcoming years.

Advanced flexibility offered by fixed bearing implants is expected to augment the product adoption

Based on implant type, the total knee replacement market size is segmented as fixed bearing implants, mobile bearing implants, medial pivot and others. Fixed bearing implants segment held the largest share in 2019. These implants offer a wide range of motion and are long lasting hence, fixed bearing implants have traditionally represented a popular choice of knee replacement prosthesis.

Furthermore, fixed bearing implant design has changed in order to negate the need for mobile bearings. For instance, Triathlon, a fixed bearing total knee replacement system manufactured by Stryker is designed to accommodate up to 20 degrees internal and external rotation. It is also designed to reduce rotational constraint compared to other systems. Triathlon is implanted in over 2 million patients across the globe. Hence, owing to these clinical advantages, fixed bearing implants are anticipated to witness a substantial growth in the upcoming years.

Several advantages offered by cruciate retaining is boosting its adoption

Based on design, the market is segmented into cruciate retaining, posterior stabilized and others. Cruciate retaining witnessed a significant growth over the historical period, wherein, the revenue in 2015 was USD 2.8 billion. Cruciate retaining offers normal knee kinematics, preserves bone and results in greater stabilization of the prosthesis. Cruciate retaining offers positive results and hence, it is preferred relatively in young people and patients with smaller knees as it is a bone conserving implant. Thus, owing to these advantages, the total knee replacement market revenue is expected to witness a significant traction in the upcoming years.

High cost effectivity and improved patient outcomes will enhance the traditional surgery market growth

Total Knee Replacement Market By Polyethylene Inserts

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Based on surgical type, the market is segmented into traditional and technology assisted surgery type. Traditional surgery held the largest revenue and was valued at USD 8.0 billion in 2019. Around 80% of total knee replacements are performed using the traditional approach. However, due to high cost of the operation and several post operational complications, the market is expected to witness slow growth and move towards the technological assisted approach that includes robotic assisted surgery and computer assisted navigational system.

Decreased risk of post-surgical infections with the usage of cemented fixation material on knee joints will enhance the market growth

Based on fixation material, the market is segmented into cemented, cementless, and hybrid. Cemented fixation material emerged as the largest segment and was valued at USD 7.2 billion in 2019. The high market value is attributed to the fact that bone cement dries within 10 minutes of application which gives assurity to patients and surgeons regarding prosthetics and its firm placement.

In addition, a small amount of antibiotic material can be added to the bone cement, which in turn helps to decrease the risk of post-surgical infections. Hence, owing to these factors, the total knee replacement market demand is expected to witness a significant uptick in the upcoming years.

High track record of metal-on-plastic implant for safety and implant life span will enhance the market growth

Based on material, the market is segmented into metal-on-plastic, ceramic-on-plastic, ceramic-on-ceramic, and metal-on-metal. Metal-on-plastic witnessed the largest revenue share in the year 2019 and is significantly growing from the historical period. The segment in 2015 and 2019 was valued at around USD 4.0 billion and USD 5.0 billion, respectively. It is one of the most common type of implants used in knee replacement procedures.

The most commonly used metals include titanium, cobalt-chromium, zirconium, and nickel. Metal-on-plastic is one of the cost-effective type of implants and has shown the longest track record for safety and implant life span. Thus, owing to these advantages, the total knee replacement market is expected to witness a significant traction in the upcoming years.

Rising demand for antioxidant polyethylene inserts due to its high strength will enhance the market growth

Based on polyethylene inserts, the market is segmented into conventional polyethylene inserts, highly cross-linked polyethylene inserts and antioxidant polyethylene inserts. Antioxidant polyethylene inserts is expected to witness a CAGR of 10.7% over the forecast period.

The high growth rate is attributed to several factors such as prevention of oxidative degradation of polyethylene, maintenance of high strength, availability of head sizes up to 44mm, and wear rates similar to metal-on-metal. Hence, owing to these factors, the segmental market is anticipated to have a significant impact on total knee replacement market growth in the coming years.

Trained professionals and availability of advanced technologies will enhance the market growth

Based on end-use, the market is segmented into hospitals, ambulatory surgical centres and others. Hospitals held the largest share and the revenue was valued at USD 7.3 billion in 2019. Majority of knee replacement surgeries are conducted in hospitals, due to the availability of advanced technologies and trained professionals in these healthcare settings. Additional provision and intensive care provided post-surgical procedures in hospital are expected to fuel the end-user segment of the market.

Presence of key players and rapidly growing prevalence of osteoporosis in the U.S. will boost the total knee replacement market share

North America held more than 50% market share in 2019 and U.S. knee replacement market is projected to exceed USD 5.8 billion by 2026. Presence of major market players and increasing prevalence of knee osteoarthritis in the region will boost the market growth. The demand for knee replacement is also since 90% of people that have undergone the knee replacement surgery experience a dramatic reduction in knee pain, thereby propelling the market growth positively. Furthermore, rising number of people suffering from obesity due to sedentary lifestyle is anticipated to increase the occurrence of bone-related problems in the country, hence fuelling the industry growth.

Germany total knee replacement market held the largest revenue share in 2019 and was valued at more than USD 430 million. Growing geriatric base coupled with rising prevalence of diseases such as osteoporosis and arthritis will fuel the market growth. Germany has top leading hospitals for orthopedics across the country. Eurostat stated that around 28.0% of total population of Germany was above 60 in 2017. Presence of organizations such as the Osteoarthritis and Musculoskeletal Diseases (ESCEO), European Society for Clinical and Economic Aspects of Osteoporosis working for reducing burden of degenerative diseases will favor the market growth. 

Execution of strategies such as partnerships and collaborations by major industry players will boost the market growth

Some of the prominent industry players operating in total knee replacement market share include Stryker, Smith & Nephew, Medacta, MicroPort Scientific, B. Braun, ConforMIS, DePuy Synthes, Corin, DJO Global and Zimmer Biomet. Development of advanced products for better outcomes and rigorous marketing are few competitive strategies adopted by market players.

Recent industry developments:

  • In March 2018, Smith and Nephew announced commercial release of bi-cruciate retaining Journey II XR total knee arthroplasty across the U.S. and Japan. The product launch was aimed at capturing large customer base with innovative product offering.
  • In October 2018, Zimmer Biomet Holdings announced to collaborate with Apple to facilitate patient and surgeon connection during the knee and hip replacement procedures. The collaboration assisted in enhancing the customer base of Zimmer Biomet.

The total knee replacement market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD from 2015 to 2026, for the following segments:

By Product

  • Primary Knee Replacement Systems
  • Revision Knee Replacement Systems
  • Partial Knee Replacement Systems

By Device Type

  • Three-compartmental Knee Implants
  • Bi-compartmental Knee Implants
  • Unicompartmental Knee Implants

By Component

  • Femoral
  • Tibial
  • Patellar

By Implant Type

  • Fixed-bearing Implants
  • Mobile-bearing Implants
  • Medial Pivot Implants
  • Others

By Design

  • Cruciate Retaining Design
  • Posterior Stabilized Design
  • Others

By Surgery Type

  • Traditional Surgery Type
  • Technology Assisted Surgery Type

By Fixation Material

  • Cemented
  • Cementless
  • Hybrid

By Material

  • Metal-on-plastic
  • Ceramic-on-plastic
  • Ceramic-on-ceramic
  • Metal-on-metal

By Polyethylene inserts

  • Conventional polyethylene inserts
  • Highly cross-linked polyethylene inserts
  • Antioxidant polyethylene inserts

By End-use

  • Hospitals
  • Ambulatory Surgery Centers
  • Others

The above information is provided for the following regions and countries:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa


Frequently Asked Questions (FAQ) :

The market size of total knee replacement crossed USD 9 billion in 2019.
The industry share of total knee replacement is projected to expand at 4.5% CAGR over 2020-2026.
Primary knee replacement systems were valued at USD 7.4 billion in 2019, says a GMI report.
Antioxidant polyethylene inserts segment of total Knee Replacement is expected to witness a CAGR of 10.7% over 2020-2026.
U.S. knee replacement industry is projected to exceed USD 5.8 billion by 2026 and North America is projected to account for more than 50% market share in the forecast timeframe.
According to this report, fixed bearing implants segment held the largest share in 2019 and is expected to continue the growth through 2026. It offers a wide range of motion and is long lasting, hence fixed bearing implants have traditionally represented a popular choice of knee replacement prosthesis.
Regionally, Germany knee replacement market was valued at more than USD 430 million in 2019.
Metal-on-plastic material segment covered a valuation of USD 5 billion in 2019.

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Premium Report Details

  • Published Date: Jan 2020
  • Pages: 850
  • Tables: 2474
  • Charts / Figures: 30
  • Companies covered: 13
  • Countries covered: 52

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