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Protein Assays Market Size, Share and Industry Analysis Report, Regional Outlook, Growth Potential, Competitive Market Share & Forecast, 2025 – 2034

Report ID: GMI4617

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Protein Assays Market Size

The global protein assays market experienced significant revenues in 2024 and is anticipated to achieve a notable CAGR from 2025 to 2034 due to the fundamental nature of these assays and proteins being critical tools in scientific research and clinical diagnostics to determine concentration, activity, and properties of proteins. The global demand for protein assays is currently growing due to an increase in applications in proteomics, biotechnology, and drug development. Our need for accurate protein quantification is increasing in the scientific community largely due to advances in drug discovery, personalized medicine, and the increasing prevalence of diseases such as cancer, cardiovascular, and neurological diseases.

The demand for high-throughput, advanced protein assays with more sensitivity, precision, and automation has grown. The factors driving the potential of the protein assays market include an increase in research regarding proteomics, an increase in investment in biotechnology and pharmaceutical industries, and a growing prevalence of chronic diseases. For instance, six out of ten Americans were reported to have at least one chronic disease, and many more were considered multi-morbid. The biotechnology and pharmaceutical industries continue to experience growth, therefore, increasing the demand for all assays and the need for accuracy in drug development processes.
 

Proteomics, the study of the proteome, or the large-scale study of proteins, their structures, and functions, has become a priority area of study in recent years because of its potential in drug development, diagnostics, and personalized medicine. At the same time, the need for effective and non-invasive disease diagnostics--particularly in current, costly burdens of diseases such as cancer and cardiovascular disease--has resulted in an increased need for accurate protein quantification tools. However, challenges still exist for this market. The high cost of some protein assay technologies, complicated protocols, and the need for technical expertise could restrain the growth of the protein assay market.
 

Protein Assays Market Trends

The market will continue to grow steadily over the next 10 years and will continue to be driven by these emerging trends. The adoption of high throughput and automated protein assays to ultimately screen protein samples more efficiently is one of the major trends that are changing the protein assay landscape. These assays represent a faster way to identify samples and are valuable tools for drug discovery and proteomics. The push for multiplex assays, which allow for the measurement of proteins effectively in a faster timeframe, is increasing the efficiency of research. The desire for personalized medicine will be a continued growth driver in the market.
 

Another key trend is the increased use of protein assays in drug development. The pharmaceutical industry has increasingly started to leverage protein assays to evaluate the pharmacokinetics and pharmacodynamics of drug candidates, and this has contributed to the rising demand. The development of protein assays in conjunction with other technologies, such as mass spectrometry and molecular imaging, is also a trend gaining popularity.
 

Protein Assays Market Analysis

The reagents segment of the market held the largest share in 2024, driven by using reagents in protein assays specific (use of antibodies, enzymes, and chemical compounds) to detect, quantify, and study protein interaction in a sample. Recently, advanced reagents were developed with greater sensitivity and specificity, which increased the growth of this category; with advancements in proteomics research, newly developed reagents detect low-abundance proteins and conduct more complex assays.
 

Research laboratories are developing new reagents to enhance protein assays and efficiency that reduce reaction and procedure time, resulting in increasing the number of samples per assay in a shorter time. The continued application of protein assays to diagnostic applications will also help propel the demand for reagents, particularly with respect to the detection of disease biomarkers.
 

The dye-binding assays segment commanded the largest share in 2024, and ongoing demand will see it grow at a good CAGR through to 2034 primarily associated with the assays deployed for determining protein in research & clinical environments. The simplicity of these assays is based on the premise that the dye binds to a protein (or a metal) - when bound the color change can be determined using a spectrophotometer. Dye-binding assays are a strong segment within the market and remain very popular due to their simplicity, low price, and ease of use. Although this segment is likely to continue increasing its market relationships at a steady level as dye-binding assays remain popular due to their simplicity and low price, there may be disruption from more sophisticated assays like ELISA and mass spectrometry.
 

The protein assays market in the drug development segment is expected to generate notable revenues through 2034. Protein assays are used to understand drug candidates' mechanisms of action, especially in target identification, biomarker discovery, and pharmacokinetics. The pharmaceutical industry increasingly relies on protein assays to determine whether drug compounds impact certain proteins, if there is therapeutic potential, and to evaluate the compounds' effects during clinical trials.
 

The rise of personalized medicine and increased focus on protein biomarkers during targeted therapies has furthered the use of protein assays for drug development. Also, pharmaceutical companies are committing to the development of novel protein assay technologies to provide increased accuracy and reproducibility. The need for novel drug therapies to address unmet medical needs will significantly impact market growth in the drug development segment of the market, within the forecast period.
 

North America protein assays market held the largest share in 2024, due to a robust healthcare system that supports life sciences, a strong pharmaceutical and biotechnology sector, and extensive medical research activity in the region. The United States, which has many major companies involved in protein assays, also accounts for a large share of the market. The overall investment in medical research in North America is a driver, along with relative consumer focus on personalized medicine and targeted therapies but the most significant influence is the rising incidence of chronic diseases, particularly cancer, cardiovascular disease, and neurological disorders.
 

Each of these diseases will generate a need for improved protein assays, both for diagnostics and treatment monitoring. The overall regulatory environment also has an effect on the protein assay market, which has the influence of the FDA and its approval and regulatory pathways for innovative protein assay technologies. As long as the biotechnology and pharmaceutical companies in North America continue to innovate and bring new products to market, the region will remain a major contributor to the protein assay market through the forecast period.
 

Protein Assays Market Share

Major players in the protein assays industry include:

  • Bio-Rad Laboratories
  • BECTON DICKINSON AND COMPANY
  • BioVision
  • Merck KGaA
  • PerkinElmer
  • Cell Signaling Technology
  • Cayman Chemical
  • Oz Biosciences
  • General Electric
  • Abcam plc
  • PROMEGA CORPORATION
  • Geno Technology
  • Thermo Fisher Scientific

To solidify their position in the market, leading companies are focusing on combining strategic partnerships, research and development (R&D) spending, and product innovation. Companies have also begun working more closely with academic universities, health systems, and research organizations to develop new protein assays and extend their customer reach. Moreover, companies are continuing to develop and monetize, new and more sensitive, and more accurate assay kits and reagents.
 

Furthermore, firms are pursuing acquisitions to inspire product growth and improve their coverage and customer scope. Leading companies including Thermo Fisher Scientific, Bio-Rad Laboratories, and Abcam, have strengthened their market footprint by investing heavily in next-generation protein analysis technologies which include multiplex assays and mass spectrometry-based proteomics. Companies will utilize their products to address the growing demand and need for protein assays in research, diagnostics, and drug development by developing better products, utilize new technologies, and expanding their geographic reach.
 

Protein Assays Industry News

  • In February 2025, Pixelgen Technologies launched a new technology designed to explore the dynamic protein interactome at the single-cell level, building on its previous advancements in DNA-based 3D proteomics. The Proximity Network Assay offered nanoscale spatial analysis of immune cell proteins on a large scale. 

 

  • In May 2023, 10x Genomics, Inc., a leader in single-cell and spatial biology, released a new Visium CytAssist Gene and Protein Expression Assay, aimed at expanding the range of spatial analysis capabilities.
Authors: Mariam Faizullabhoy
Authors: Mariam Faizullabhoy ,
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