Organs-on-chips Market Size & Share 2024 – 2032
Market Size by Type [Product (Liver, Lung, Heart, Kidney), Service], Material (PDMS, Polymer, Glass), Model Type (Single, Multi-organ), Application (Drug Discovery, Toxicity Testing, Personalized Medicine), End User.
Report ID: GMI7964
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Published Date: January 2024
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Report Format: PDF
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Authors:
Monali Tayade, Jignesh Rawal
Organs-on-chips Market Size
Organs-on-chips Market size was valued at USD 116.5 million in 2023 and is expected to record over USD 1.4 billion by 2032 driven by the increasing demand for more accurate and reliable in-vitro models of human organs for drug discovery, toxicity testing, and disease modelling.
Organs-on-chips Market Key Takeaways
Market Size & Growth
Key Market Drivers
Challenges
Organs-on-chips are microfluidic devices that hold the potential to revolutionize the pharmaceutical and healthcare industries by providing more physiologically relevant R&D platforms. Moreover, this technology offers a significant benefit for potentially minimizing the need for animals in medical research, aligning with ethical practices. For instance, the Humane Society International stated that over 115 million animals are utilized for clinical testing worldwide. The strong ability to replicate human organs affordably also makes these devices promising tools in non-animal alternative testing for drug discovery.
However, the high cost of developing and manufacturing sophisticated devices can be a major barrier, limiting the product adoption in well-funded research institutes and large pharmaceutical companies. Regulatory challenges are also a major obstacle, as certification and approval processes for new technologies are lengthy and rigorous. Limited awareness and acceptance among the general scientific and medical communities will further hinder the market expansion.
Organs-on-chips Market Trends
The rising prevalence of chronic diseases is increasing the need for rapid drug discovery methods, driving the necessity for drug toxicity identification, technological progress, and the introduction of new products by major market players. For instance, Emulate Inc.'s alveolus lung-chip and airway lung-chip models, helped in COVID-19 research. These innovative organ-on-chip technologies supported in enhancing the early infectious disease clinical studies for expediting the pandemic research efforts.
The growing advancement and the support by regulatory authorities are accelerating the development and adoption of advanced organ-on-chip technologies. For instance, in January 2023, FDA Modernization Act 2.0 approval aimed to accelerate the organ-on-chip integration in pharmaceuticals, using innovations in testing methods for ethical and streamlined drug development. Advanced technologies are providing an opportunity for the pharmaceutical industry to expedite drug development while reducing reliance on animal studies.
Organs-on-chips Market Analysis
Based on type, the market size from the product segment is expected to generate a revenue of USD 944.7 million by 2032. The precise prediction of airborne nanoparticle absorption and accurate replication of the inflammatory response to microbial pathogens has stirred the widespread adoption of lung-on-chip models. The prevalence of pulmonary diseases, especially tuberculosis, has surged the demand for effective disease management, contributing to segment growth. According to the Center for Disease Control and Prevention (CDC), two billion people, accounting for one-fourth of the world’s population, get infected with tuberculosis (TB)annually.
Based on material, the organs-on-chips market from the polydimethylsiloxane (PDMS) segment is expected to record USD 646.9 million by 2032. Microfluidic organ-on-chip platform using PDMS has gained rapid popularity and widespread acceptance due to its compatibility with high-resolution microstructures and nanostructures through replica molding. PDMS is also recognized for its biocompatibility, optical transparency, and gas permeability, making it well-suited for biological applications.
Based on model type, the single-organ model segment is anticipated to generate USD 881.5 million by 2032 attributed to their specificity and focused applications. The single-organ model maintains the ability to replace organ-level responses in a controlled environment, leading to widespread product adoption.
Based on application, the organs-on-chips market from the drug discovery segment will exhibit over 32% CAGR through 2032. The trials in novel drug discovery, characterized by rising R&D costs and low success rate in clinical trials is propelling the demand for advanced and precise predictive preclinical in-vitro models.
Based on end-user, the organs-on-chips market value from the pharmaceutical and biotechnology companies segment reached USD 73.3 million in 2023. Several pharmaceutical and biotechnology companies are actively seeking innovative solutions to bridge the translational gap between preclinical and clinical drug development to reduce attrition rates. Substantial investments are helping them to prioritize R&D while focusing on personalized medicine, and consistently launching new products. Strong emphasis on enhancing preclinical testing efficiency will drive the segment growth.
North America organs-on-chips market size was USD 44.9 million in 2023 and is anticipated to generate USD 533.9 million by 2032 attributed to the rising prevalence of chronic diseases. For instance, in June 2023, the FDA granted a partial option award to further propel the development of organ chips for radiation countermeasure research, evaluating efficacy and screening experimental compounds for Medical Countermeasures (MCM). Furthermore, the growing investments by the public and private institutes, exemplified by the National Institutes of Health (NIH) funding for biotechnology will signify continuous regional growth.
Organs-on-chips Market Share
Leading organs-on-chips industry players are focusing on R&D, product innovation, and strategic collaborations to gain a competitive edge and meet the growing demand for advanced in-vitro models. These firms are also eyeing investments to proliferate their portfolio.
Organs-on-chips Market Companies
Prominent participants operating in the organs-on-chips industry are:
Organs-on-chips Industry News:
The organ on chip market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2018 to 2032 for the following segments:
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Market, By Type
Market, By Material
Market, By Model Type
Market, By Application
Market, By End-user
The above information is provided for the following regions and countries:
Research methodology, data sources & validation process
This report draws on a structured research process built around direct industry conversations, proprietary modelling, and rigorous cross-validation and not just desk research.
Our 6-step research process
1. Research design & analyst oversight
At GMI, our research methodology is built on a foundation of human expertise, rigorous validation, and complete transparency. Every insight, trend analysis, and forecast in our reports is developed by experienced analysts who understand the nuances of your market.
Our approach integrates extensive primary research through direct engagement with industry participants and experts, complemented by comprehensive secondary research from verified global sources. We apply quantified impact analysis to deliver dependable forecasts, while maintaining complete traceability from original data sources to final insights.
2. Primary research
Primary research forms the backbone of our methodology, contributing nearly 80% to overall insights. It involves direct engagement with industry participants to ensure accuracy and depth in analysis. Our structured interview program covers regional and global markets, with inputs from C-suite executives, directors, and subject matter experts. These interactions provide strategic, operational, and technical perspectives, enabling well-rounded insights and reliable market forecasts.
3. Data mining & market analysis
Data mining is a key part of our research process, contributing nearly 20% to the overall methodology. It involves analysing market structure, identifying industry trends, and assessing macroeconomic factors through revenue share analysis of major players. Relevant data is collected from both paid and unpaid sources to build a reliable database. This information is then integrated to support primary research and market sizing, with validation from key stakeholders such as distributors, manufacturers, and associations.
4. Market sizing
Our market sizing is built on a bottom-up approach, starting with company revenue data gathered directly through primary interviews, alongside production volume figures from manufacturers and installation or deployment statistics. These inputs are then pieced together across regional markets to arrive at a global estimate that stays grounded in actual industry activity.
5. Forecast model & key assumptions
Every forecast includes explicit documentation of:
✓ Key growth drivers and their assumed impact
✓ Restraining factors and mitigation scenarios
✓ Regulatory assumptions and policy change risk
✓ Technology adoption curve parameter
✓ Macroeconomic assumptions (GDP growth, inflation, currency)
✓ Competitive dynamics and market entry/exit expectations
6. Validation & quality assurance
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Our triple-layer validation process ensures maximum data reliability:
✓ Statistical Validation
✓ Expert Validation
✓ Market Reality Check
Trust & credibility
Verified data sources
Trade publications
Security & defense sector journals and trade press
Industry databases
Proprietary and third-party market databases
Regulatory filings
Government procurement records and policy documents
Academic research
University studies and specialist institution reports
Company reports
Annual reports, investor presentations, and filings
Expert interviews
C-suite, procurement leads, and technical specialists
GMI archive
13,000+ published studies across 30+ industry verticals
Trade data
Import/export volumes, HS codes, and customs records
Parameters studied & evaluated
Every data point in this report is validated through primary interviews, true bottom-up modelling, and rigorous cross-checks. Read about our research process →