Nutrigenomics-Based Personalized Supplements Market Size - By Type, By Application, By End Use, Growth Forecast, 2025 - 2034

Nutrigenomics-Based Personalized Supplements Market Size

The global nutrigenomics-based personalized supplements market size was valued at USD 1.6 billion in 2024. The market is expected to grow from USD 1.8 billion in 2025 to USD 6.7 billion in 2034, at a CAGR of 15.8%, according to the latest report published by Global Market Insights Inc.

The market is experiencing transformative growth because of the continued advancement in genomic sciences, the emergence of AI-driven diagnostic tools, and a growing propensity toward preventive healthcare. The convergence of nutrigenomics, digital health, and personalized nutrition has ushered in new avenues for consumer engagement and interaction, particularly among consumers interested in health and wellness and who have an affinity for technology.
 

Several macro and micro economic factors are driving acceleration of global demand. More than 60% of global deaths are attributed to non-communicable diseases (NCDs) that can be largely mitigated or prevented with appropriate dietary and lifestyle change. Personalized supplements derived from nutrigenomic insights are playing a vital role as a model of healthcare where genetic susceptibility has caused NCDs to be a main concern.
 

In addition, the market is gaining traction because of increased awareness surrounding the human genome, more widespread availability of direct-to-consumer (DTC) genetic testing, and the decreased cost of sequencing. Companies like 23andMe, MyDNA, and DNAfit have democratized genetic testing, and supplement companies like Rootine and Persona Nutrition have developed custom formulas based on that knowledge.
 

From a technology standpoint, the integration of artificial intelligence (AI) and machine learning is changing the way genetic data is analyzed to recommend specific nutrient compositions. There are now new systems that can process thousands of SNPs (Single Nucleotide Polymorphisms) and metabolomic biomarkers to accrue precise recommendations. Many tech-oriented companies are also taking the mHealth approach, which is pushing compliance and engagement through data tracking, interactive dashboards and app- or web-based subscription services.
 

North America has the highest contributing region, boasting over 38% market share in 2024. The region can essentially be attributed to high healthcare spending, substantial consumer digital health adoption, and the growing availability of nutrigenomic testing services. Meanwhile, Europe is anticipated to be the fastest-growing region, fueled by regulatory support for personalized medicine, as well as the functional food sector. The Asia-Pacific region offers the most promising growth opportunities, driven by urbanization, higher disposable income, and unserved customer bases in India, China, South Korea, and Japan.
 

There is a remarkable shift, among both millennials and elderly, of selecting genetically enriched fortified nutrition vs generic supplements. Additionally, consumer preferences of dietary supplements appear to have changed (i.e. clean label, allergen-free, plant-based), increasingly aligned with consumers' genetic methylation profiles and microbiome profiles.
 

Nutrigenomics-Based Personalized Supplements Market Trends

• One core trend is the integration of multi-omics approaches, including genomics, microbiomics, metabolomics, and proteomics, that are facilitated through artificial intelligence and machine learning algorithms to produce highly personalized supplement recommendations. Companies, such as GenoPalate and InsideTracker, are utilizing data from thousands of SNPs (single nucleotide polymorphisms) in combination with blood biomarkers to offer real-time adaptive supplementation protocols. 
   
• As consumer health data, particularly genetic data, will remain central to discovering personalized nutrition services, so too with continued pressure for more rigorous regulatory mechanisms and data oversight. Governments throughout the EU and North America will be lobbying for data compliance with established norms, such as GDPR, HIPAA, and other data privacy practices.
   
• Furthermore, in 2025, the FDA is expected to launch a new regulatory review process that will facilitate better classification and review of genetic-based nutritional foods to minimize misinformation for consumers. Companies selling testing and supplements will increasingly devote resources toward data security infrastructure and transparency in compliance to earn trust.
   
• Consumer expectations are shifting from basic vitamins to condition-based, -gene informed nutrition plans that target specific areas of concern including metabolic syndrome, stress, aging, and sleep health. A McKinsey Health report published (2024) states that 74% of consumers prefer supplement plans that are guided by their daily routines and health goals versus generic plans. Startups like ZOE and legacy players like Nestlé Health Science (Persona), are now looking at developing SKUs (stock-keeping units) that are tailored to genetic testing-based use-cases or phenotypic traits.
   
• With increasing disposable income and smartphone penetration, companies are actively engaging in B2B partnerships with clinics, pharmacies, insurers, and/or wellness providers in the emerging markets of India, Brazil, and Southeast Asia. Companies are also embedding their platform in telemedicine and e-pharmacy platforms to improve access both for genetic testing and supplement subscription models. For example, in Australia, MyDNA partnered with pharmacies to embed test-based supplement recommendations at point of sale.
  
   

Nutrigenomics-Based Personalized Supplements Market Analysis

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Based on type, the nutrigenomics-based personalized supplements market is divided into genetic testing kits & reagents, AI-powered interpretation platforms, and personalized supplement formulations. Genetic testing kits & reagents segment generated a revenue of USD 481.8 million in 2024 and is expected to reach USD 2.4 billion in 2034 at a CAGR of 16%.
 

• The genetic testing kits & reagents segment captures the largest market share within the category of the nutrigenomics-based personalized supplements market, with a projected market share of 35% in 2024. This market share is largely due to the important nature of genetic testing in enabling personalized nutrition. Personalized nutrition fundamentally relies on genetic data collected via testing kits; without genomic data, downstream data on supplement formulations and lifestyle changes would not be possible.
   
• Advancements in microarray technology, targeted SNP panels, and at-home testing via saliva have improved genetic testing ease of use and access. For example, companies—including myDNA, DNAfit, and Nutrigenomix—are offering kits that cost less than $100 and have intuitive means of collecting samples followed by analysis on an app-based mobile device. Such a price shift has dramatically increased the rate of uptake across all consumer segments, especially D2C.
   
• The emergence of accurate, non-invasive, CLIA-certified kits with timely turn arounds of 5-10 days have increased the validity of these kits. Improvements in reagent stability, the miniaturization of test components, and improvements in sample processing, have all enhanced the performance, validity, and scalability of testing. Companies have also begun to bundle kits with supplements, offering subscriptions or recurring revenue streams.
   

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Based on application, the nutrigenomics-based personalized supplements market is divided into obesity & weight management, cardiovascular health, diabetes & metabolic disorders, sports nutrition & performance, and general wellness & longevity. In 2024, obesity & weight management segment held major market share, accounted for 24.2% market share.
 

• The obesity & weight management category commands the most significant market share. This dominance is primarily driven by the global epidemic of obesity, which has been reported to impact on over 1.9 billion adults globally by the WHO. Personalized nutrition interventions based on genetic information have the potential to reverse widespread disease in the future.
   
• One common application in this area is analyzing metabolic gene variants (the FTO, MC4R and UCP1 genes), which relate to fat storage, satiety, and energy expenditure. Companies such as DNAfit, myDNA, and GenoPalate, rely on these variants in developing supplements and diets tailored to individual users' physiology to achieve sustainable weight loss.
   
• Another strong use case is appetite regulation where AI-supported technology recommends nutrients - chromium, 5-HTP and/or a personalized fiber blend, based on serotonin-related genes activity. This targeted nutrition helps users reduce cravings and calories far more efficiently than generic diet plans.
   
• Furthermore, personalization for carbohydrate and fat metabolism allows the consumer to personalize their macronutrient intake, supported by multiple peer-reviewed studies, based on genetic responsiveness. Supplement recommendations often include personalized amounts of L-carnitine, omega-3s and/or thermogenic compounds.
   

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• The U.S. nutrigenomics-based personalized supplements market generated a revenue of USD 497.6 million in 2024. The U.S. market is projected to grow at a CAGR of 16% and is expected to reach USD 2.2 billion by 2034. North America continues to lead the global market for nutrigenomics-based personalized supplements due to its well-established healthcare system, the early adoption of genetic testing directly from the consumer, and its strong wellness sector.
   
• The U.S. has been and continues to be an innovator in the category of nutrigenomics-based supplements—specifically by incorporating genetic technologies into lifestyle management—due to the healthy competition between small, start-up, and larger corporations. A relevant example of investment which could indirectly grow market opportunities and leverage the knowledge regarding gene-nutrient interactions was initiated by the NIH with the All of Us research program that has the goal of collecting genomic data from one-million Americans.
   
• Additionally, a changing consumer preference for both preventive health and applied technological products, such as wearables linked to a mobile supplement plan (e.g., InsideTracker), continue to build momentum into the market. The region has seen growing strategic actions as well, such as Nestlé Health Science acquiring Persona Nutrition. Such moves in the region indicate confidence for the long term future of the nutrigenomics supplement category.
   
• Europe nutrigenomics-based personalized supplements market generated a revenue of USD 400 million in 2024. Europe market is projected to grow at a CAGR of 15.1% reaching USD 1.6 billion by 2034. Europe is a growing progressive center for regulatory and clinical validation in the nutrigenomics arena.
• The European Union has led the way on its regulation regarding genetic testing, functional foods and personalized nutrition under EFSA guidelines, building a more systematic and credible environment for both companies and consumers. With their high digital health literacy and interest in lifestyle medicine, countries like Germany, the Netherlands, and the Nordics are leading the way in demand. Companies like DNAfit (UK) and Nutrition Hub (Germany) are responding with well-designed, scientific backed products.
   
• The demand for cognitive and longevity-enhancing personalized supplements is further heightened as personalized aging solutions are falling into focus for the aging European population; these products are customized by genome-based markers on things like methylation and inflammation levels.
   
• Asia Pacific nutrigenomics-based personalized supplements market generated a revenue of USD 352 million in 2024. Asia Pacific market is projected to grow at a CAGR of 16.6% reaching USD 1.6 billion by 2034. The Asia Pacific region is seeing the quickest uptake in adoption fueled by a large population base, digitization of services, and growing spending by the middle class on wellness. South Korea and Japan are leading the consumer awareness and integration of biotechnology, with various companies providing personalized probiotic and traditional supplement formulations based on genetic and microbiome diagnostics.
   
• China's "Healthy China 2030" policy shows an intent at the national level to incorporate health tech—including genetic testing and personalized nutrition, into a baseline of health care offerings. In parallel, Indian start-ups are quickly gaining traction in urban metro areas, particularly around genetic lifestyle management and genomic nutrition platforms combined with Ayurveda. There are still some consumer fears regarding genetic data, leaving openings for local, smaller, encrypted platforms that have stronger trust metrics.
   
• Latin America represents an embryonic, but growth-ready market. Brazil and Mexico have started to signal themselves as a market for nutrigenomics. Economic recovery from COVID has likely fueled interest in immune-boosting and personalized wellness. Notably, the expanding number of private clinics and health insurance companies offering preventive health-aimed programs is leading to a growing interest in personalized diagnostics.
   
• However, the consideration of affordability is very much on consumers' mind, leading to developments in lower-cost (but still valid) genetic testing packages that accompany supplement subscriptions. Startups in Brazil are using genetic research done locally and dietary preferences to launch products that have culturally related products—this is a significant consideration for consumers that varies considerably across societies, cultures and context throughout the region.
   
• The Middle East and Africa are still at the open-ended developmental end of the spectrum. Interest is picking up, particularly in the UAE, Saudi Arabia and South Africa. There is national investment into digital health technologies and personalized wellness as part of national rollouts, such as Saudi Vision 2030. The UAE has invested in its genomic research centers to explore application across healthcare. This is starting to influence the development of personalized nutrition.
   

Nutrigenomics-Based Personalized Supplements Market Share

The competitive environment of the nutrigenomics-based personalized supplements industry is characterized by high levels of innovation, speed to market, and vertical integration between genetic testing and supplements delivery platforms. The market share, while fragmented, is concentrated with the top five firms, Persona Nutrition, Zoe, InsideTracker, Rootine, and DNAfit, representing over 40% of market share by 2024.
 

Persona Nutrition, which is owned by Nestlé Health Science, has the largest global footprint in the market employing large-scale operations, R&D, and integrated supplement fulfillment is also a distinct advantage. InsideTracker and DNAfit have also maintained competitive stances with a focus on bioinformatics-driven profiling for personalized supplements, and partnerships with wearables technology solution providers for AI-enabled health dashboards.
 

Innovation and data science capabilities remain the primary differentiators. For example, Rootine utilizes genetic markers, blood test markers, and lifestyle data in its precision-dosed capsules. myDNA, on the other hand, positions itself in pharmacogenomics, and emphasizes nutraceutical crossover. Companies are increasing customer lifetime value through subscriptions. Strategic alliances and joint ventures with biotech labs to develop new products or M&A activity to establish a foothold are also common. Notable transactions include Nestlé's ownership of Persona and Pfizer's exploratory research with personalized nutrition startups.
 

Nutrigenomics-Based Personalized Supplements Market Companies

Major players operating in the nutrigenomics-based personalized supplements industry are:

• Persona Nutrition
• Zoe
• InsideTracker
• Rootine
• DNAfit
• myDNA
• GenoPalate
• Nutrigenomix
• Sun Genomics
• Elysium Health
   

Persona Nutrition: Persona Nutrition is a premier personalized supplements company owned by Nestlé Health Science since 2019. They create daily vitamin packs for consumers formulated with the use of artificial intelligence based on lifestyle habits, health goals, and consideration of any drug-nutrient interactions, all which stem from a five-minute online quiz that the consumer takes to help generate their personalized supplement packs. From a strategic perspective, they benefit from being backed by the credibility and global supply chain of Nestlé, which translates into the ability to grow and penetrate high scalability markets, especially in North America and Europe.
 

InsideTracker: InsideTracker combines data from genetics, blood biomarkers and data from fitness trackers to develop personalized diet and supplement recommendations. It has a strong value proposition in the details they offer, which is attractive to athletes and biohackers because of its scientific rigor and greater detail around those recommendations. It also has an advantageous partnership with wearable platforms like Fitbit and Garmin that make it part of the ecosystem and strengthens its customer retention.
 

Rootine: Rootine uses a combination of genetics, blood micronutrient analysis, and lifestyle surveys to develop precision micronutrient packs. It is unique in relying on a precision dosing model, which gives consumers a scientific option that does not attempt to one-size-fit (the) supplements. Rootine primarily targets high-performing professionals and health-conscious consumers in the U.S. and E.U. markets.
 

myDNA: myDNA, which operates from Australia, offers personalized reports on supplements and wellness based on DNA and pharmacogenomics. The brand is scaling through partnerships with retail pharmacies and white-label services, while also finding differentiation by providing lifestyle genomics solutions beyond that of nutrition, including lifestyle and fitness and medication.
 

Nutrigenomics-Based Personalized Supplements Industry News:

• In September 2025, Rootine launched its new line of epigenetic-based supplements that leverage biological age testing data to deliver personalized anti-aging support.
   
• In August 2025, InsideTracker collaborated with Apple Health to offer bio-tracking and personalized nutrition dashboard capabilities based on real-time biomarkers in conjunction with wearables.
   
• In June 2025, Persona Nutrition worked with Walgreens to initiate a pilot genetic testing kit in-store tied to personalized subscription supplements.
   
• In May 2025, myDNA officially expanded into Southeast Asia via contractual arrangements with pharmacies in Thailand and Singapore to provide DNA-based nutrition kits.
   
• In March 2025, DNAfit announced it had launched a corporate wellness genomic testing package targeting multinational employers across Europe, with a focus on preventative strategies in nutrition.
   
• In January 2025, Zoe announced it completed a Series C funding round of USD 125 million to support its microbiome-based personalized supplement platform, as well as entry into the U.S. retail market.
   

The nutrigenomics-based personalized supplements market research report includes in-depth coverage of the industry, with estimates & forecast in terms of revenue (USD Million) from 2021 to 2034, for the following segments:

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Market, By Type

• Genetic testing kits & reagents
  • Targeted SNP panels
  • Whole genome sequencing
  • Pharmacogenomic testing
  • Epigenetic analysis
• AI-powered interpretation platforms
  • Multi-omics integration platforms
  • Predictive analytics engines
  • Clinical decision support systems
  • Consumer mobile applications
• Personalized supplement formulations
  • Precision vitamins & minerals
  • Targeted nutraceuticals
  • Microbiome-informed probiotics
  • Performance optimization formulas

Market, By Application

• Obesity & weight management
  • Metabolic gene variants analysis
  • Appetite regulation optimization
  • Dietary response personalization
  • Exercise & lifestyle recommendations
• Cardiovascular health
  • Lipid metabolism optimization
  • Inflammation response management
  • Dietary fat response personalization
  • Homocysteine metabolism support
• Diabetes & metabolic disorders
  • Glucose metabolism optimization
  • Insulin sensitivity enhancement
  • Carbohydrate response personalization
  • Diabetic complication prevention
• Sports nutrition & performance
  • Muscle composition optimization
  • Energy metabolism enhancement
  • Recovery & stress response
  • Injury prevention & rehabilitation
• General wellness & longevity
  • Aging & cellular health
  • Immune system optimization
  • Cognitive function enhancement
  • Stress response management

Market, By End Use

• Direct-to-consumer platforms
  • Comprehensive multi-omics providers
  • Specialized testing services
  • Supplement-first brands
  • Subscription box models
• Healthcare provider channel
  • Primary care integration
  • Specialty clinics & functional medicine
  • Hospital systems & health networks
  • Registered dietitians & nutritionists
• Corporate wellness programs
  • Large enterprise programs
  • Mid-market employer benefits
  • Health plan integration
  • Workplace wellness vendors
• Retail & e-commerce
  • Pharmacy chains
  • Health food retailers
  • General e-commerce platforms
  • Specialty retail locations

The above information is provided for the following regions and countries:

• North America 
  • U.S.
  • Canada 
• Europe
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Rest of Europe
• Asia Pacific 
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • Rest of Asia Pacific
• Latin America 
  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America
• Middle East and Africa 
  • Saudi Arabia
  • South Africa
  • UAE
  • Rest of Middle East and Africa