Lyophilization Equipment Market Size By Product (Tray Style Freeze Dryers, Manifold Freeze Dryers, Rotary Freeze Dryers), By Scale of Operation (Bench Top, Pilot Scale, Industrial Scale), By Application (Pharmaceutical, Biotechnology, Biomedical, Food Processing), Industry Analysis Report, Regional Outlook, Application Potential, Price Trends, Competitive Market Share & Forecast, 2019 – 2025
Published Date: Sep 2019 | Report ID: GMI3577 | Authors: Sumant Ugalmugle, Rupali Swain
Lyophilization Equipment Market was valued at over USD 4.9 billion in 2018 and is projected to witness 8.4% CAGR from 2019 to 2025.
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Rapid expansion of pharmaceutical and food industry has created lucrative growth opportunities for the lyophilization equipment market players. Rising demand for freeze-drying equipment used for production of quality products with better shelf life has elevated the use of freeze dryers, thereby augmenting the market growth over the coming years.
Increasing focus on therapeutic and biopharmaceutical products such as monoclonal antibodies will positively impact the market growth. Key factor for the rising popularity of lyophilized products is higher temperature stability along with longer shelf life. Freeze drying helps in preserving the physical structure of the drug by heating heat-sensitive pharmaceutical products at low temperature. Thus, growing awareness about benefits of lyophilized products including increased efficiency in comparison to air and desiccant drying will drive the growth of the market.
Rising number of contract manufacturing companies and availability of lyophilization services in the market are some of the major factors expected to boost the market growth. The equipment suppliers and manufacturers are following an array of process analytical technology (PAT) to develop superior freeze-drying system to optimize their operations. With the growing demand of preserved food and biopharmaceutical products, there will be substantial growth in the use of aseptic packaging, hence stimulating the business growth. Freeze drying technique is widely used in pharmaceutical industry due to the delivery of biologically active and stable products with longer shelf life by this equipment.
Stringent regulations for approval of lyophilization equipment in pharmaceutical and food industry may hamper the growth of lyophilizer market during the projected timeline. Furthermore, high cost of equipment maintenance and lack of skilled workforce especially in developing countries will further restrain the market growth.
|Base Year:||2018||Market Size in 2018:||4.9 Billion (USD)|
|Historical Data for:||2014 to 2018||Forecast Period:||2019 to 2025|
|Forecast Period 2019 to 2025 CAGR:||8.4%||2025 Value Projection:||8.5 Billion (USD)|
|Pages:||130||Tables, Charts & Figures:||100|
|Geographies covered (18):||U.S., Canada, Germany, UK, Spain, Italy, The Netherlands, France, China, Japan, India, Australia, Brazil, Mexico, Argentina, South Africa, Saudi Arabia, UAE|
|Segments covered:||Product, Scale of Operation, Application and Region|
|Companies covered (10):||Telstar, GEA Group, Labconco, SP Industries, Inc., Optima Pharma, HOF Sonderanlagenbau GmbH, Buchi, Millrock Technology Inc., Scala Scientific, ZIRBUS Technology GmbH|
|Pitfalls & Challenges:||
Lyophilization Equipment Market, By Product
Manifold freeze dryer market will witness growth of 9.0% during the forecast period. Increasing use of these freeze dryers to produce active pharmaceutical ingredient (API) can be attributed to the substantial growth of the segment. Moreover, manifold freeze dryer is cost-effective and easy-to-operate over other freeze-drying equipment, that will surge the use of manifold freeze dryers over the coming years, thereby positively stimulating the industry growth.
Rotary freeze dryer market is projected to reach over USD 191.0 million by 2025. Increasing use of lyophilization technique for drying cubes, pellets and other aqueous solution has augmented the use of rotary freeze dryers. These type of freeze dryers provide more uniform drying in the product, imparting longer shelf life, that will positively impact segmental growth.
Lyophilization Equipment Market, By Scale of Operation
Bench top freeze dryer market is estimated to witness more than 9.5% CAGR during the projected timeline. The economical and simple means of stabilizing and preserving fragile and biological materials are the major factors driving the market growth. Bench top lyophilizers are ideal for small scale operations, equipped with customized tray spacing and vacuum lyophilization technology. Thus, increasing use of bench top freeze dryer for small scale operations will lead to robust growth of the market.
Pilot scale freeze dryer market accounted for over USD 144.0 million revenue in 2018 owing to the rising adoption of such type of freeze dryer in small scale production unit and research laboratories. Moreover, the system is equipped with advanced temperature control system and provides better service life, easy installation and low maintenance feature of the equipment, that will further augment the market growth.
Lyophilization Equipment Market, By Application
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The biotechnology segment accounted for over 15.0% market share of global lyophilization equipment industry in 2018. Use of freeze-dried biological products such as interferon alfa, streptokinase-anti blood clot medicine and wasp venom allergenic extract has strengthened the growth of biotechnology segment. Rising demand of lyophilized vaccines including typhoid, measles and meningococcal polysaccharide vaccine will drive the market growth. Furthermore, increasing production of freeze-dried probiotic powders will positively affect the biotechnology segment growth in the future.
Food processing industry held major revenue share in 2018 and is estimated to progress at 8.3% CAGR over the forecast period. Growing preference for frozen and preserved food among the consumers has led to the increased use of lyophilization equipment in the food processing industry. Moreover, growing urbanization has escalated the consumption of preserved food. Increased use of freeze dryer in coffee and tropical fruits has encouraged the manufacturers to use lyophilization technique in the food industry. Thus, food processing segment is expected to witness lucrative growth in the future.
Lyophilization Equipment Market, By Region
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Increasing demand of freeze-dried products and growing awareness about benefits of lyophilization has stimulated the demand for lyophilized products in the U.S. resulting in over USD 2.5 billion market size by 2025. Several biotechnology and pharmaceutical companies are adopting advanced technology to preserve high value products such as antibodies, proteins, vaccines and blood plasma. Presence of major market players in the country and increasing investment in research and development of advanced lyophilized products will contribute to the U.S. lyophilization equipment market growth over the anticipated period.
India accounted for around 12% industry share of Asia Pacific market in 2018 and is anticipated to witness substantial growth in the future. Rapid expansion of pharmaceutical and food industry in the country will accelerate the market growth. Additionally, rising investment by major market players focusing on strengthening their market position will stimulate the business growth over the foreseeable period.
Competitive Market Share
Some of the major market players of global lyophilization equipment market are Telstar, GEA group, Labconco, SP Industries, Optima Pharma, Buchi, HOF Sonderanlagenbau GmbH, Millrock Technology, Inc. and Scala Scientific. These companies are adopting various business strategies to strengthen their market position as well as increase company’s product revenue by investing significantly in research and development of advanced freeze-dried products. New product launch and strategic alliances are the key strategies adopted by these industry players.
Recent industry developments:
- In June 2019, Lyophilization Services of New England (LSNE) completed its acquisition of Sterile injectables manufacturing facility in Leon, Spain. The acquisition aimed at expanding the service portfolio and strengthening the market position of LSNE in Europe.
- In March 2018, GEA launched a new RAY PP (Pilot Plant) batch freeze dryer for small scale companies and R&D drying of food products such as fruits, coffee, vegetables, meat, pet food and other products including enzymes, lactic acid bacteria and lactoferrin. The new product launch helped the company in elevating its market position as well as broaden its product portfolio.
Lyophilization Equipment Industry Background
The history of lyophilization can be traced back to 15th century, that witnessed the use of traditional methods of freeze drying. In 1890, Altman used free drying technique for preparation of histological sections, but this method went unnoticed for almost 40 years. The technique later was rediscovered by Shackell for the preservation of biologicals. During World War 2, modern lyophilization technique was developed for preservation of plasma, to transport samples from the U.S. to Europe. Following the path of innovation, the freeze-drying technique was commercially developed to preserve chemically stable blood without refrigeration. In 1935, first commercial lyophilization equipment was developed. Later, this technique was used to preserve bones, penicillin and numerous other biological samples. In 1964, freeze drying technique gained momentum in food industry, and Nestle adopted freeze-drying technique to produce instant coffee. Today, with rapid expansion of pharmaceutical industry and rising demand of freeze-dried products, freeze drying technique is widely used for the preserving high valued pharmaceutical products. It has several applications in pharmaceutical, food, ceramics and many other fields. For instance, Bosch developed a new freeze dryer to stabilize thermolabile and active ingredients such as, vaccines, antibodies and oncological medications in April 2018. Thus, growing demand of advanced lyophilized products and collaborations between major market players will create lucrative opportunity for the industry growth.
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