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The application segment is bifurcated into immunoprecipitation and antibody purification. Antibody purification includes specific isolation and specific enrichment of antibodies from polyclonal antibodies, ascites fluid and cell culture supernatant of monoclonal antibodies. Rising demand for monoclonal antibodies has triggered the commercial production and purification of mAb using protein A resins.
Antibody purification market held over USD 469 million market size in 2019. The importance of antibody purification is continuously growing owing to achievement of excellent grade purity of antibodies. In addition, wide use of chromatography, technological advancements and practical uses of antibody purification will increase its preference over others. Moreover, increasing demand of drug development will spur the market growth in the forthcoming years.
In terms of product segment, the report covers natural and recombinant resins. Recombinant protein A resins market reported more than 9% CAGR during the forecast period. Recombinant proteins are used to prepare nanoparticles for protein drug carrier. Thus, with expanding innovation in drug discovery, the market demand will increase through 2026.
Recombinant protein A is mainly used to improve solubility and to normalise sensitivity of alkaline solutions. With expanding pharmaceuticals industry and increasing technological advancements in novel drug development, the segment will proceed at significant rate.
Agarose-based matrix type accounted for over USD 499 million revenue in 2019. It is gaining massive popularity and will continue to show growth due to wide use in pharmaceutical and biotechnology industry. Owing to its high gelling strength at low concentrations, anti-convection medium for gel electrophoresis, suitable pH range and superior mechanical strength, this segment will witness positive growth.
As per the study analysis, end-use segment of protein A resins market is categorized as biopharmaceutical companies, clinical research laboratories, academic research institutes and contract research organizations. Biopharmaceutical companies segment accounted for over USD 453 million revenue size in 2019.
Due to rising prevalence of various chronic diseases and increasing demand of better treatment methods, biopharmaceutical industry will foresee high demand for protein A resins. Increasing demand for protein engineering with various advancements will further boost segmental growth. Growing application in chromatography in biopharmaceutical industry will also provide substantial segment growth.
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Regionally, North America held substantial revenue share in 2019 and will witness around 9% CAGR during the analysis period. Regional growth is mainly attributed to presence of major market players constantly investing into research and development activities. Furthermore, rising prevalence of autoimmune and orphan diseases and increasing demand of better treatment methods will boost the regional market growth in the region.
Presence of major industry players in the U.S. and increasing incidence of chronic diseases will favor the U.S. protein A resins market growth. Moreover, growing demand of technologically advanced products in this country will highly impact the market growth. Furthermore, increasing drug delivery and development will offer positive market growth in the country.