DNA Synthesis Market Analysis

DNA Synthesis Market Analysis

By service, the DNA synthesis market is classified into oligonucleotide synthesis and gene synthesis. Oligonucleotide synthesis segment dominated the market in 2022 with a revnue share of 52.6%. Increasing demand for synthetic biology is driving the demand for oligonucleotides. Oligonucleotides are essential tools for gene synthesis, DNA sequencing, and genetic engineering, supporting advancements in fields such as medicine and biotechnology. Moreover, companies are entering into strategic initiatives to launch novel products, which is expected to drive the segment. For instance, in October 2022, Bachem entered into collaboration with Eli-Lilly and Company for the development and manufacturing of APIs that are based on oligonucleotides. Such initiatives by market players will drive the segmental growth.
 

By method, the DNA synthesis market is classified into solid phase synthesis, PCR-based enzyme synthesis and chip-based synthesis. The solid phase synthesis segment accounted over 36.6% of the market share in 2022 and is projected to witness robust CAGR over the analysis timeframe. Solid-phase DNA synthesis allows researchers to design and synthesize DNA sequences with high precision and flexibility. It enables the creation of custom DNA molecules with specific sequences, lengths, modifications, and labelling, tailored to the needs of various applications. The method is highly efficient with quicker turnaround time. Additionally, solid-phase DNA synthesis can be easily scaled up to accommodate larger quantities of DNA. Such benefits associated with solid-phase synthesis method is expected to propel the segmental demand.
 

Based on application, the DNA synthesis market is bifurcated into research & development, diagnostics and therapeutics. The research and development segment held the largest share of 43.6% in 2022. DNA synthesis is a fundamental tool for biotechnology-based research. DNA synthesis is widely used in the discovery and development of new drugs. They are also utilized in the development of diagnostic tests for genetic diseases, infectious diseases, and cancer. For instance, in November 2021, DNAScript declared that it received a grant of USD 2.2 million from the National Human Genome Research Institute as a support fund for the development of next-generation printers that enzymatically print synthetic nucleotides. Thus, such aforementioned funding coupled with multiple applications of DNA synthesis in R&D activities will drive the market statistics.
 

DNA synthesis market by end-use is classified as academic & research institutes, biopharmaceutical companies, contract research organizations. The academic and research institutes is expected to reach over USD 11 billion by 2032. DNA synthesis plays a crucial role in academic and research institutes across various fields. Synthetic DNA enables customization that is essential for complex research studies. The high accuracy of DNA synthesis provides researchers with the flexibility to create complex DNA sequences that may be difficult or impossible to obtain through traditional cloning methods. Therefore, high adoption of DNA synthesis has revolutionized molecular biology research leading to new discoveries and breakthroughs, thereby contributing to the market expansion.
 

North America dominated the global DNA synthesis market with a revenue share of 38.4% in 2022. High market share is attributed to growing R&D investments and presence of key market players in the region. Also, initiatives by governments and collaborations between market players further strengthen the market growth. For instance, in April 2021, DNA Script entered into partnership with Moderna, Inc. with a USD 5 million grant from the U.S. Defense Advanced Research Projects Agency to develop a prototype for rapid mobile manufacturing of vaccines and therapeutics as part of the Defense Advanced Research Projects Agency's (DARPA) Nucleic Acids On-Demand World-Wide (NOW) Program. Therefore, constant support from government along with rising incidence of various chronic & infectious diseases as well as rising demand for effective diagnosis and treatment is expected to boost the market growth.