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Tramadol Drug Market - By Dosage Form (Tablet, Capsule, Liquid, Suspension), Route of Administration (Oral, Parenteral), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Online Pharmacy), Global Forecast, 2023-2032

  • Report ID: GMI6684
  • Published Date: Sep 2023
  • Report Format: PDF

Tramadol Drug Market Size

Tramadol Drug Market size was valued to be USD 4.5 billion in 2022 and is expected to reach USD 8.6 billion in 2032, growing at a CAGR of 6.8% from 2023 to 2032. The market's significant growth is primarily driven by the rising prevalence of pain disorders such as arthritis, neuropathy, or fibromyalgia.

Tramadol Drug Market

For instance, according to the Good Body stats, at least 10% of the world’s population is affected by chronic pain, and it has been estimated that 1 in every 5 adults suffer from pain and some acute pains which are undiagnosed till it becomes chronic. Similarly, increase in geriatric population coupled with rise in lower back pain which requires surgery, therapy, and pain management drugs is also boosting the market. Moreover, growing healthcare infrastructure in emerging markets, rising awareness pertaining to pain management, and increasing R&D activities are expected to fuel the market’s growth during the forecast period.

Tramadol is a drug used to relieve moderate to severe pain. It belongs to a class of drugs known as opioid analgesics or opioids. It works by binding to opioid receptors in the brain and spinal cord, which helps to alter the way the body perceives and responds to pain. It is used to manage various types of pain, such as post-surgical pain, chronic pain associated with conditions like osteoarthritis or neuropathy, and pain from injuries.

COVID-19 Impact

The COVID-19 pandemic had a moderately positive impact on tramadol drug market. Due to safety restrictions enforced by governments, many clinics and pain services were no longer open for public. However, the increased adoption of telemedicine and virtual consultations during the pandemic had led to greater awareness and education about various treatment options, including pain management. As many people worked from home, ergonomic challenges and musculoskeletal issues became more common. This resulted in increased pain complaints and the need for pain management, potentially involving tramadol.

Also, the pandemic led to increased stress, anxiety, and mental health issues for many individuals, which exacerbated pain conditions. Few COVID-19 patients experienced lingering symptoms, such as body aches and pain, which required tramadol to reduce the symptoms. Furthermore, many elective surgeries and medical procedures were postponed to conserve healthcare resources and reduce the risk of transmission. As a result, some patients experienced prolonged pain and required tramadol for pain relief. Thus, the aforementioned factors contributed to the expansion of market.

Tramadol Drug Market Driving Factors

The major factor driving the growth of the market is the increasing prevalence of pain and pain disorders globally.For instance, according to Centers for Disease Control and Prevention (CDC), in the U.S. adults, about 58.5 million people had doctor-diagnosed arthritis and by 2040, an estimated 78.4 million adults will have doctor-diagnosed arthritis. Therefore, pain can have substantial impacts on bodily function and limitations on various activities, affecting various physiological and psychological processes. It causes hyperalgesia, sleep disturbance, immune system suppression, and muscle tension. The complications can vary depending on the age of the affected individual.

Tramadol Drug Market Restraint

While tramadol plays a crucial role in pain management, the various side effects associated with the drug can impact drug uptake and market dynamics. Though these side effects can vary in severity and occurrence among individuals, some common ones include nausea, vomiting, dizziness and drowsiness, that can impair a person's ability to concentrate and perceive the surrounding. Headaches, dry mouth, and constipation are relatively common whereas, skin reactions, including itching and rashes, are possible side effects but less common.

Moreover, tramadol, like other opioids, can slow down breathing in some cases, particularly when taken in high doses or combined with other central nervous system depressants, such as alcohol and seizures. Thus, such factors may hamper the market progress.

Tramadol Drug Market Analysis

Tramadol Drug Market, By Dosage Form, 2021 - 2032 (USD Billion)

Based on the dosage form, the tramadol drug market is segmented into tablet, capsule, suspension, liquid, and other dosage forms. The tablet segment held largest business share of 50% in 2022. Tablets are a well-established and widely accepted oral dosage form. They are easy to swallow and convenient for patients to take, making them a preferred choice for many individuals, including those who need to manage chronic pain. Also, they offer precise dosage control, allowing for consistent and accurate administration of tramadol. This is crucial in pain management to ensure that patients receive the appropriate amount of medication for their pain relief.

Moreover, tablets are relatively easy for patients to manage and adhere to their prescribed treatment regimen. Patients can easily keep track of when they need to take their medication, which is essential for effective pain management. Therefore, due to their familiarity, ease of use, and ease of storage, tablets will contribute to expand the market expansion.

Tramadol Drug Market Revenue Share, By Route of Administration, (2022)

Based on the route of administration, the tramadol drug market is classified into oral, parenteral, and other route of administration. The oral segment led the global market in 2022, with a market size of USD 3.6 billion. The oral route is the most common and familiar method of taking medications for patients. It is convenient and non-invasive, allowing patients to self-administer their medication easily. Many patients are comfortable with this mode of administration, which can lead to better adherence to prescribed treatments. The oral route provides flexibility in dosing. Tramadol can be formulated in various dosage forms, including immediate-release and extended-release tablets or capsules. This allows to tailor the dosage regimen to individual patient needs, ensuring optimal pain management. Moreover, it is well-suited for oral administration because it is absorbed effectively through the gastrointestinal tract.

Based on the distribution channel, the tramadol drug market is segmented into hospital pharmacy, retail pharmacy, and online pharmacy. The hospital pharmacy segment is expected to reach USD 5 billion by 2032. Hospital pharmacies play a key role in the market, as they are integral to the distribution, organisation, and administration of the tramadol within the healthcare ecosystem. Hospitals are often hubs of acute pain management, complex medical procedures due to accidents, and post-surgical recovery, all of which frequently involve the administration of tramadol drug. Also, the diverse patient base in hospital increases the likelihood of drug being offered to various age groups.

North America Tramadol Drug Market Size, 2020 – 2032 (USD Billion)

 In 2022, the North American tramadol drug market held the largest share of 38.6% and is anticipated to show considerable growth during the analysis period. The region has a relatively high prevalence of pain conditions, including acute and chronic pain resulting from various factors such as surgical procedures, injuries, and medical conditions. For instance, according to Centers for Disease Control and Prevention (CDC), nearly 20.9% of U.S. adults experienced chronic pain, and 6.9% experienced high-impact chronic pain. Thus, the demand for pain management medications like tramadol is driven by the significant patient population in need of pain relief.

Additionally. The market is being driven by favourable initiatives and aids from governments as well as significant research & development expenditures in the region. Further, the region's prominence on patient-focused care, along with the availability of tramadol, specialized medical centers, and awareness, further drives the demand for market in the region.

Tramadol Drug Market Share

The top players in the global tramadol drug market are:

  • Zydus Cadila
  • Purdue Pharma
  • Mankind Pharma Ltd
  • Mundipharma
  • Amneal Pharmaceuticals
  • Par Pharmaceuticals
  • Vertical Pharmaceuticals
  • Grunenthal Group
  • Nippon Shinyaku Co., Ltd.

These companies are implementing several strategies such as collaborations, acquisitions, partnerships, mergers, and product launches to maintain a competitive edge in the industry.

Tramadol Drug Market Industry News:

  • In September 2020, Athena Biosciences received the U.S. FDA approval for its Qdolo (tramadol) oral solution. The solution is utilized for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. This enabled company to add value to its business segment and expand the company’s revenue.
  • In November 2018, Cipla acquired U.S.-based Avenue Therapeutics. The acquisition gave Cipla access to specialty drug tramadol delivered intravenously (IV) to manage post-operative pain. This increased the Cipla’s product portfolio.

The tramadol drug market report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2018 to 2032 for the following segments:

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By Dosage Form

  • Tablet
  • Capsule
  • Liquid
  • Suspension
  • Other dosage forms

By Route of Administration

  • Oral
  • Parenteral
  • Other routes of administration

By Distribution Channel

  • Hospital pharmacy
  • Retail pharmacy
  • Online pharmacy

The above information is provided for the following regions and countries:

  • North America 
    • U.S.
    • Canada 
  • Europe
    • Germany
    • UK
    • France
    • Spain
    • Italy
    • Rest of Europe 
  • Asia Pacific
    • China
    • Japan
    • India
    • Australia
    • Rest of Asia Pacific 
  • Latin Americ 
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • Rest of Middle East & Africa


Authors: Mariam Faizullabhoy, Gauri Wani

Frequently Asked Questions (FAQ) :

Tramadol drug market size was USD 4.5 billion in 2022 and will reach USD 8.6 billion by 2032 due to the rising prevalence of pain disorders, such as arthritis, neuropathy, or fibromyalgia worldwide.

The tablet dosage form segment held 50% share of the tramadol drug industry in 2022 and will witness significant growth from 2023-2032 on account of the precise dosage control of tablets that to allow foroffer consistent and accurate administration of tramadol.

North America recorded 38.6% share of the tramadol drug industry in 2022 and is expected to incur appreciable growth from 2023-2032 owing to the prevalence of pain conditions, including acute and chronic pain among consumers in the region.

Zydus Cadila, Purdue Pharma, Mankind Pharma Ltd, Mundipharma, Amneal Pharmaceuticals, Par Pharmaceuticals, Vertical Pharmaceuticals, Grunenthal Group, and Nippon Shinyaku Co., Ltd. are some of the major tramadol drug companies worldwide.

Tramadol Drug Market Scope

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Premium Report Details

  • Base Year: 2022
  • Companies covered: 9
  • Tables & Figures: 206
  • Countries covered: 19
  • Pages: 120
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