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Barbiturate Drugs Market - By Drug Type (Long-Acting, Short-Acting, Ultra-Short Acting Barbiturate, Combination Drugs), Application (Insomnia, Epilepsy, Sedation), Distribution Channel (Hospital, Retail Pharmacies) – Global Forecast (2024 – 2032)

  • Report ID: GMI8668
  • Published Date: Mar 2024
  • Report Format: PDF

Barbiturate Drugs Market Size

Barbiturate Drugs Market size was valued at USD 472.9 million in 2023 and is estimated to grow at a CAGR of 3% between 2024 and 2032 to reach USD 613.7 million by 2032. Barbiturate drugs belong to a class of central nervous system depressants known for their sedative, hypnotic, and anticonvulsant properties. They exert their effects by enhancing the activity of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, resulting in sedation, muscle relaxation, and anxiety reduction.

Barbiturate Drugs Market

Initially widely used for medical purposes such as treating insomnia, anxiety, epilepsy, and anesthesia for surgical procedures, barbiturates have seen a decline in use due to their potential for abuse and overdose. The increasing prevalence of neurological disorders has become a significant driver for the market.

According to the World Federation of Neurology in 2023, neurological disorders rank as the second-highest cause of death and the primary cause of disability worldwide. It's estimated that over 40% of the global population currently experiences some form of neurological condition, with this burden expected to nearly double by 2050. As a result, there is a notable surge in demand for innovative treatments and therapies to address the rising incidence of neurological disorders.

Furthermore, rising geriatric population, introduction of a novel drug delivery system, technological advancements in drug delivery, among other contributing factors are estimated to propel the growth of the market in the forthcoming years.

Barbiturate Drugs Market Trends

The introduction of novel drug delivery systems represents a paradigm shift in pharmaceutical innovation promising a multitude of advantages across various facets of healthcare. These cutting-edge systems revolutionize the way medications are administered offering precise control over drug release, targeted delivery to specific sites within the body, and enhanced therapeutic efficacy.

  • Advanced drug delivery systems play a crucial role in improving medication efficacy by facilitating targeted delivery to specific sites within the body, thereby maximizing therapeutic effects while minimizing side effects.
  • Novel drug delivery systems often provide convenient administration routes such as transdermal patches or long-acting injectables, which can enhance patient adherence to treatment regimens.
  • Additionally, controlled-release formulations and targeted delivery mechanisms help reduce systemic drug exposure, thereby minimizing the risk of adverse reactions and enhancing overall safety profiles. These advanced formulations also offer precise control over drug release kinetics, improving drug absorption, distribution, metabolism, and excretion profiles, thereby enhancing drug efficacy and predictability.

Barbiturate Drugs Market Analysis

Barbiturate Drugs Market, By Drug Type, 2021 – 2032 (USD Million)

Based on drug type, the market is classified into long-acting barbiturate, short-acting barbiturate, ultra-short acting barbiturate, and combination drugs. The long-acting barbiturate segment held a market size of USD 200.4 million in 2023.

  • Long-acting formulations provide sustained drug release over an extended period ensuring prolonged therapeutic effects without the need for frequent dosing. This leads to improved patient compliance and convenience.
  • These formulations maintain stable blood levels of the barbiturate drug reducing fluctuations in drug concentration and minimizing the risk of breakthrough symptoms or adverse effects.
  • Additionally, maintaining consistent drug levels in the bloodstream, long-acting barbiturates offer more reliable symptom control, crucial for optimal management in sleep disorder, which estimated to reach USD 73.5 billion by 2032, such as insomnia, thereby fostering the segment landscape.


Barbiturate Drugs Market, By Application (2023)

Based on application, the barbiturate drugs market is segmented into insomnia, epilepsy, sedation, and other applications. The epilepsy segment is estimated to account for a market size of USD 303 million by 2032.

  • Barbiturate drugs particularly phenobarbital utilized as anticonvulsants in the treatment of epilepsy with phenobarbital being one of the oldest and most frequently prescribed medications for seizure management.
  • Further, epilepsy treatment drugs such as phenobarbital exert their anticonvulsant effects by enhancing the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the brain, reducing neuronal excitability, and suppressing seizure activity, thereby augmenting the segment growth of the market.

Based on distribution channel, the barbiturate drugs market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies. The retail pharmacies is estimated to account for a market size of USD 274.7 million by 2032.

  • Retail pharmacies are widely accessible to the general population providing convenient locations for patients to fill their prescriptions for barbiturate drugs.
  • Retail pharmacies frequently provide prescription management services such as refill reminders and medication synchronization programs, aiding patients in maintaining consistency with their barbiturate therapy.
  • Moreover, retail pharmacies usually stock various generic barbiturate drugs offering cost-effective alternatives for patients unable to afford brand-name medications, thereby propelling the growth of the market.


North America Barbiturate Drugs Market, 2021 – 2032 (USD Million)

North America barbiturate drugs market accounted for USD 191.6 million revenue in 2023 and is predicted to witness substantial market growth.

  • North America boasts a well-developed healthcare infrastructure with modern facilities and sophisticated medical technology facilitating the effective diagnosis and treatment of conditions requiring barbiturate therapy.
  • Furthermore, upsurge in the incidence of insomnia, epilepsy, and anxiety disorders are anticipated to drive market growth. For instance, according to the Centers for Disease Control and Prevention (CDC) recent statistics approximately 14.5% of U.S. adults experienced difficulty falling asleep, while 17.8% reported trouble in staying asleep.
  • Moreover, the region is home to leading pharmaceutical companies and research institutions, fostering innovation in drug development and enabling the creation of novel formulations and delivery systems for barbiturate medications.

Barbiturate Drugs Market Share

The barbiturate drugs industry is competitive in nature, with several large multinationals and small and mid-sized companies competing in the industry. The development and launch of novel advanced devices based on different technologies is among a key market strategy. Some of the leading industry players have a notable presence in the market.

Barbiturate Drugs Market Companies

Some of the eminent market participants operating in the barbiturate drugs industry include:

  • Abbott Laboratories
  • AbbVie Inc.                        
  • Akorn, Inc.                        
  • Centurion Healthcare Private Limited                             
  • Ethypharm                        
  • GSK plc.                            
  • Intas Pharmaceuticals Ltd.
  • Johnson & Johnson                       
  • Merck & Co., Inc.                         
  • Novartis AG                       
  • Par Pharmaceutical Companies, Inc.                             
  • Pfizer Inc.                          
  • Samarth Life Sciences Pvt Ltd.                           
  • Sun Pharmaceutical Industries Ltd.                     
  • Teva Pharmaceutical Industries Limited

Barbiturate Drugs Industry News:

  • In June 2021, Ethypharm announced that it had entered into a definitive agreement to acquire Altan Pharma, a specialty pharmaceutical company specializing in the development, manufacturing, and marketing of injectable medicines for hospital use. This acquisition bolstered Ethypharm's portfolio and market presence, allowing it to expand its offerings in the hospital pharmaceutical sector.

The barbiturate drugs market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD Million from 2021 – 2032 for the following segments:

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Market, By Drug Type

  • Long-acting barbiturate                
  • Short-acting barbiturate               
  • Ultra-short acting barbiturate                 
  • Combination drugs

Market, By Application

  • Insomnia      
  • Epilepsy        
  • Sedation       
  • Other applications

Market, By Distribution Channel

  • Hospital pharmacies           
  • Retail pharmacies              
  • Online pharmacies

The above information is provided for the following regions and countries:

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • Japan
    • China
    • India
    • Australia
    • South Korea
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
  • Middle East and Africa
    • South Africa
    • Saudi Arabia
    • UAE
    • Rest of Middle East and Africa


Authors: Mariam Faizullabhoy, Gauri Wani

Frequently Asked Questions (FAQ) :

Barbiturate drugs market size was USD 472.9 million in 2023 and is expected to register 3% CAGR from 2024-2032 owing to the surge in demand for innovative treatments and therapies to address the rising incidence of neurological disorders worldwide.

The long-acting barbiturate segment recorded USD 200.4 million in 2023 and is expected to register an appreciable CAGR from 2024-2032 due to their ability to provide sustained drug release over an extended period ensuring prolonged therapeutic effects.

North America barbiturate drugs industry reached USD 191.6 million in 2023 and is expected to register a commendable CAGR from 2024-2032 due to the presence of a well-developed healthcare infrastructure with modern facilities and sophisticated medical technology in the region.

Johnson & Johnson, Merck & Co., Inc., Novartis AG, Par Pharmaceutical Companies, Inc., Pfizer Inc., Samarth Life Sciences Pvt Ltd., Sun Pharmaceutical Industries Ltd., and Teva Pharmaceutical Industries Limited, are some of the major barbiturate drugs companies worldwide.

Barbiturate Drugs Market Scope

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Premium Report Details

  • Base Year: 2023
  • Companies covered: 15
  • Tables & Figures: 219
  • Countries covered: 22
  • Pages: 190
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