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Mice Model Market Size By Mice Type (Inbred, Outbred, Knockout, Hybrid), By Technology (CRISPR, Microinjection, Embryonic Stem Cell Injection, Nuclear Transfer), By Application (Research and Development, {Infectious Disease, Immunological Diseases, Cancer, Cardiovascular Diseases, Diabetes, Genetic Diseases, Neurological Diseases}, Production and Quality Control, Academics), By Use (Human, Veterinary), By End-use (Companies {Pharmaceutical, Biotechnology, Cosmetics}, Organizations {Government, Non-government}, Academic and Research Institutes, Contract Research Organizations (CROs)), Industry Analysis Report, Regional Outlook, Application Potential, Competitive Market Share & Forecast, 2020 – 2026

  • Report ID: GMI4473
  • Published Date: Dec 2020
  • Report Format: PDF

Industry Trends

Mice Model Market size exceeded USD 7.6 billion in 2019 and is poised to grow at over 6.9% CAGR between 2020 and 2026. Growing incidences of chronic disorders and increasing demand for effective therapeutic drugs have positively impacted the market growth.

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Technological advancements in gene editing has significantly aided the scientists in research and development of novel drugs, leading to increased utilization of mice models. These models are extensively used in research studies of various fields such as oncology and immunology. Rising demand for personalized medicines has further led to an increase in development of genetically modified humanized mice model market.

The outbreak of coronavirus leading to the ongoing COVID-19 pandemic is an unprecedented public health concern. There is a rising need for development of vaccines and therapeutic agents to combat the current pandemic and to prevent the re-emergence of COVID-19 as humans do not have pre-existing immunity to SARS-CoV-2. The demand for humanized ACE2 mouse models is increasing owing to the need to conduct research experiments. Therefore, government and scientific research institutions are bound to increase research investments to develop vaccines and treatments against COVID-19. These factors are potentially augmenting the mice model market demand. Generation of mouse-adapted viruses have also led to increase utilization of several inbred mouse strains in SARS research. However, some of the market players are unable to meet the surging demand and several research institutions are unable to operate properly due to the ongoing pandemic. Overall, the ongoing pandemic has minimally impacted the mice model market growth.

Rise in the advancements in gene editing tools will enhance the market growth

Rise in the advancements in gene editing tools will stimulate the mice model market growth. CRISPR also known as clustered regularly interspaced short palindromic repeats, associated protein (Cas9) technology has revolutionised genome editing. Several novel applications of CRISPR/Cas9 in a broad range of diseases have demonstrated its efficiency and have been used in-vivo mice models significantly. For instance, application of viral mediated delivery of CRISPR system to somatic cells of adult mice has resulted in generation of Eml4-Alk-driven lung cancer mouse model to study the disease characteristics.

Additionally, transgenic mice have been created by incorporation of Cas9 into mouse zygotes for understanding pathophysiology of cardiovascular diseases. CRISPR-Cas9 System has also been used in generation of Kcnj13 mutant mice to study ophthalmic diseases. The technology has further assisted researchers to generate different types of immunodeficient models of mice.

Growing preference for inbred models of mice

Inbred mice model market revenue in 2019 was more than USD 2 billion led by increasing usage of inbred mice in the research of pharmacology and cardiovascular diseases and to study the responses of monoclonal antibodies. Inbred mice have also proven to be powerful tools in genetics studies of complex diseases, due to which there is an increased demand for inbred mice.

Furthermore, they are also used in transgenic research owing to the consistency of genetic background. In addition, inbred mice are cost-effective as compared to mutant humanized mice. They are genetically stable, economical and have fully developed immune system.

Increasing adoption of microinjection technology

Microinjection segment revenue in the mice model market was over USD 1.4 billion in 2019 due to the efficacy and flexibility of the technique in producing genetically modified mice. Microinjection technique enables the incorporation of DNA into each cell of developing mice with high regeneration potential. Host-range independency of microinjection technique is leading to its wide acceptance and utilization.

Additionally, significant developments in microinjection technique including automated micromanipulations coupled with the control and standardization of cell preparation are contributing to increased adoption of this technique. Thus, genetically engineered transgenic mouse models are being generated at a moderate pace using microinjection technique for cardiovascular research.

Increase in investments in companies will drive the mice model market revenue

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Companies segment value was around USD 4.5 billion in 2019 on account of the increasing adoption of mice models for drug discovery along with development and production of novel products by pharmaceutical and biotechnology companies. Biotechnology and pharmaceutical companies focus towards utilizing these models for developing novel drugs to seek profitable business share. Pharmaceutical companies are also involved in preclinical examination as well as toxicity testing of drugs. Moreover, basic and applied medical and veterinary research projects are also supported by biotechnology companies.

Growing need for mice models in academics

Academics segment is anticipated to register growth of 7.9% in the mice model market during the forecast period impelled by growing demand for mice models in academic institutions. The academic institutions use preserved mice models for pharmacology education to understand the drug toxicity behaviour.

For instance, Yale university developed a novel HIV drug suppressing HIV virus in humanized mice that has proven to be less toxic. A similar study was performed at the University of Pittsburgh and the Temple University for removal of HIV DNA from the genomes of humanized mice. Moreover, these models are used in academics to provide education and training to a new generation of scientists as well as facility managers.

Rise in demand for disease treatment in animals

Veterinary segment in the mice model market is projected to expand at 6.7% CAGR through 2026. Growing prevalence of various animal disorders such as seizures and severe infectious diseases have led to an increase in R&D activities to develop veterinary medicines. Presence of veterinary contract research organizations offering mice models for veterinary drug discovery with related services will expand the demand in the future. Furthermore, research projects involving the use of mice models for veterinary research are well funded by National Institutes of Health (NIH).

Increasing prevalence of chronic disorders in North America

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U.S. dominated the North America mice model market and was valued at USD 6 billion in 2019 attributed to the high prevalence of chronic diseases including diabetes and viral diseases. Several research organizations in the country are focusing on development of effective therapeutic drugs for the treatment of viral diseases.  Various mutant mouse models are being generated in large volumes by high-throughput mutagenesis programs in the U.S. through Knockout Mouse Project (KOMP).  Mutant Mouse Regional Resource Center (MMRRC) in the U.S. serves as repositories for mouse strains that are important for use in biomedical research in order to meet the demand and supply of mouse models. Presence of well-established industry players along with state-of-the-art healthcare facilities in the country will further fuel the market demand.

UK mice model market size was around USD 198 million in 2019. Mice models in UK are being used on a large scale for research and development of novel vaccines. Increasing prevalence of Alzheimer disorders in the country is leading to the growth in research and development activities, thereby augmenting the demand for mouse models. For instance, the European Union, sponsors the research organization consortiums for research and development of mouse models for Alzheimer’s disease. In addition, the European Association for Cancer Research is engaged in organizing various workshops pertaining to the technologies used in the field of innovative mouse models across the country. This initiative is expected to propel the market growth in the country.

Presence of strong market players implementing strategic initiatives

Some of the major players operating in the mice model market include Charles River, Envigo, Taconic Biosciences, Inc, genOway, Janvier Labs, and Hera BioLabs. These companies are undertaking various strategic acquisitions, mergers, collaborations and partnerships in order to expand customer base and strengthen their industrial position. These major market players are also engaged in research and development in order to develop novel mouse models. The investment by these players in the recent years has further created opportunities for global expansion of the market.

The mice model market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD from 2015 to 2026, for the following segments:

Market, By Mice Type

  • Inbred
  • Outbred
  • Knockout
  • Hybrid
  • Others

Market, By Technology

  • Microinjection
  • Embryonic Stem Cell Injection
  • Nuclear Transfer
  • Others

Market, By Application

  • Research & Development 
  • Infectious Disease
  • Immunological Diseases
  • Cancer
  • Cardiovascular Diseases
  • Diabetes
  • Genetic Diseases
  • Neurological Diseases
  • Others 
  • Production and Quality Control
  • Academics
  • Others

Market, By Use

  • Human
  • Veterinary

Market, By End-use

  • Companies 
  • Pharmaceutical
  • Biotechnology
  • Cosmetics
  • Others 
  • Organizations
  • Government
  • Non-government 
  • Academic and Research Institutes
  • Contract Research Organizations (CRO)

The above information is provided for the following regions and countries:

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Spain
    • Italy
    • Switzerland
    • Netherlands
    • Czech Republic
    • Poland
    • Belgium
    • Finland
    • Hungary
    • Denmark
    • Ireland
    • Sweden
  • Asia Pacific
    • China
    • Japan
    • Australia
    • South Korea
    • New Zealand
    • Taiwan
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE
    • Israel


Authors: Sumant Ugalmugle, Rupali Swain

Frequently Asked Questions (FAQ) :

The global market size for mice model was over USD 7.6 billion during 2019 and will expand at more than 6.9% CAGR through 2026 with the growing need for developing therapeutic drugs.
The inbred mice model segment share was valued at over USD 2 billion in 2019 and will grow due to their use in research of cardiovascular diseases, pharmacology and to study monoclonal antibody responses.
The microinjection segment reached USD 1.4 billion in 2019 owing to the efficacy and flexibility of the technology to produce modified mice.
The veterinary segment is expected to witness over 6.7% CAGR between 2020-2026 with the need for medicines to treat numerous animal disorders like infections and seizures.
The U.S. market size had reached over USD 6 billion during 2019 owing to major focus of research organizations on developing treatment for viral diseases and chronic disorders.

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  • Base Year: 2019
  • Companies covered: 8
  • Tables & Figures: 769
  • Countries covered: 30
  • Pages: 366
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