Organ-on-chips Market Size, Industry Analysis Report, Regional Outlook, Application Potential, Price Trends, Competitive Market Share & Forecast, 2021 – 2027
Report ID: GMI3811
Organ-on-chips Market size is projected to experience significant growth from 2019 to 2025.
The rising demand for substitutes required for animal testing in order to reduce the risk of life-threatening side effects of certain drugs is a major factor driving the growth of global organ-on-chips business in the coming years. The adoption rate of these microfluid chips is increasing, as the traditional animal model often fails to mimic human physiology. Furthermore, to accelerate the process of new drug development and high demand for personalized medicine will escalate market growth.
Rising investment in research and development of organs-on-chips will positively impact industry growth. For instance, in March 2017, a team of scientists from Northwestern University developed EVATAR, a 3-D organ-on-chip model of the female reproductive tract for studying the effects of drugs and diseases including the cervical cancer. Thus, increasing investment in the development of novel organ-on-chips models will assist the industry growth over the upcoming period. Additionally, the surging initiatives by prominent institutions, to invest and investigate drug repositioning by using organ-on-chips models will assist in market growth. However, high cost and interference of microfluids in obtaining the end results will negatively impact the market growth to certain extent over the coming years.
The liver-on-chip segment is expected to dominate the market over the upcoming years owing to its simplicity and ability of the chip to maintain hepatic metabolic activity. The increasing failures of animal testing due to hepatotoxicity will spur the demand for liver-on-chip devices for drug testing. Moreover, liver-on-chip has the ability to maintain a microscopic environment. High demand for liver cells and less availability of human liver cells for testing will stimulate the market growth by employing chips instead of human liver cells.
Drug discovery will hold a significant share of the application category due to increasing focus on development of novel drugs. Furthermore, rising demand for more prognostic in-vitro methods for drug development in pharmaceutical companies and growing proclivity for alternatives to traditional cell culture methods are some of the factors driving the growth of drug discovery segment over the foreseeable period.
Pharmaceutical and biotechnology companies will maintain dominance over the forecast years due to rising investment made by these companies in research and development activities. The animal model often fails to mimic human physiology. Organ-on-chips has the potential to identify and validate the efficacy and safety of drugs in the early stages, thereby increasing the chances of success of clinical trials. Thus, to obtain more reliable results and to develop novel drug entities the adoption of organs-on-chips will increase by the pharmaceutical and biotechnology companies.
U.S. organ-on-chips market is forecasted to witness a significant growth owing to the availability of new and technologically advanced organ-on-chips in the U.S. market. Additionally, the availability of large number of services provided by key players including customized designing of new chips and increase in toxicological testing of chemicals will positively impact the market over the coming years. Suitable infrastructure and favorable government initiatives in the country in terms of investment towards basic drug development and research will further escalate the industry growth. For instance, the U.S. FDA granted USD 5.6 million to The Wyss Institute for testing its organ-on-chip technology developed for evaluation of drugs that will counteract the effect of radiations on human physiological responses.
India organ-on-chips market is expected to grow at a significant pace over the forecast period owing to the developing healthcare industry and rising healthcare expenditure. Players involved in the manufacturing of organs-on-chips products are eyeing upon the developing regions to increase their market footprint will positively impact the growth of Indian market. For instance, in May 2019, CN Bio signed a distribution agreement with AXT for distribution of organ-on-chip systems in the Asia Pacific region.
Some of the major market players involved in the global organ-on-chips market are InSphero, Emulate Inc., MIMETAS, BioreclamationIVT. ELEVATING SCIENCE, Nortis, MesoBioTech, TissUse Gmb among others. Organizations are adopting strategies such as collaboration to advance development of novel products in order to increase their market share as well as expand product portfolio. For instance, in May 2018, AstraZeneca and Emulate entered into a strategic agreement to advance organ-on-chips technology. This strategic agreement helped AstraZeneca to more accurately predict the adverse effects of drugs in the early stage of clinical trials.
Organ-on-chips Market by Type, 2014-2025 (USD Million)
Organ-on-chips Market by Application, 2014-2025 (USD Million)
- Toxicology research
- Physiological model development
- Drug discovery
Organ-on-chips Market by End-use, 2014-2025 (USD Million)
- Academic and research institutes
- Pharmaceutical and biotechnological institutes
The above information is provided for the following regions and countries:
- North America
- Asia Pacific
- Latin America
- Middle East and Africa
- South Africa
- Saudi Arabia
- Emulate Inc.
- BioreclamationIVT. ELEVATING SCIENCE
- TissUse Gmb
- TARA Biosystems, Inc.
- CN Bio Innovations
- SynVivo, Inc.
- Organovo Holdings Inc.
- Kirkstall Ltd
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