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Antibody Production Market Size - By Process (Upstream Processing {Bioreactors}, Downstream {Chromatography Systems}, Filtration {Systems}), Type (Monoclonal, Polyclonal), End-use & Global Forecast 2024 – 2032

  • Report ID: GMI6490
  • Published Date: Aug 2023
  • Report Format: PDF

Antibody Production Market Size

Antibody Production Market size accounted for USD 16.1 billion in 2023 and is estimated to grow at 11.7% to reach USD 44 billion by 2032. Targeted therapies offer a highly specific and personalized approach to treating various diseases, such as cancer and autoimmune disorders, by precisely targeting the underlying molecular mechanisms responsible for these conditions.
 

Antibody Production Market

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This approach minimizes damage to healthy cells and tissues, resulting in reduced side effects and enhanced therapeutic outcomes. As the understanding of disease pathways and molecular interactions continues to advance, the demand for specialized antibodies tailored to these specific targets has surged.
 

Antibody production refers to the controlled and deliberate generation of specific proteins known as antibodies, which are crucial components of the immune system. These antibodies, also referred to as immunoglobulins, are produced by specialized immune cells called B cells (B lymphocytes) in response to the presence of foreign substances, known as antigens. The process of antibody production involves the recognition of antigens by B cells, followed by their activation and subsequent differentiation into antibody-secreting plasma cells.
 

COVID-19 Impact

The emergence of the COVID-19 pandemic had a positive impact on antibody production market. With efforts to counter the virus gaining global attention, there was a significant rise in the demand for high-quality antibodies for diagnostic tests, treatments, and vaccine development. This demand prompted researchers and biotechnology companies to innovate and streamline antibody production processes, resulting in accelerated methods for generating large quantities of specific antibodies. Furthermore, the urgency of the situation also facilitated regulatory flexibility, allowing for faster approvals of new antibody-based diagnostics and therapies.
 

Antibody Production Market Trends

The increasing expenditure on research and development (R&D) by pharmaceutical and biotechnology companies is one of the significant development drivers for the antibody production industry. As these industries strive to develop novel therapeutics and diagnostics, antibodies play a pivotal role due to their specificity and versatility. The rising R&D investments facilitate the discovery of new target molecules and disease pathways, which in turn fuels the demand for specialized antibodies that can precisely interact with these targets. This demand drives innovation in antibody production techniques, leading to the development of more efficient and scalable processes. Furthermore, elevated R&D spending fosters collaborations and partnerships between academia, research institutions, and private enterprises, enabling the pooling of expertise and resources for accelerated antibody discovery and development.
 

Antibody Production Restraint

The antibody production market faces a significant challenge due to the substantial expenses linked with manufacturing antibodies. Creating and producing antibodies, particularly those customized for targeted therapies and diagnostic purposes, involves intricate and resource-demanding procedures. The initial phase of research and development necessitates significant investments in technology, staff, and equipment. This is followed by complex production processes, including cell cultivation, purification, and quality assurance, which require specialized facilities and skilled personnel. Moreover, the costs are further heightened by the need to uphold rigorous quality benchmarks and adhere to regulatory standards, often demanding extr resources for documentation, testing, and validation.
 

Antibody Production Market Analysis

Antibody Production Market, By Process, 2021 - 2032 (USD Billion)
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By process, the antibody production market is classified into downstream processing, upstream processing, and filtration. The downstream processing segment accounted for 61.7% of the industry share in 2022. The growing requirement for accurate and high-quality antibody-based treatments is highlighting the significance of this essential phase in biomanufacturing, involving antibody purification, separation, and formulation. Furthermore, downstream processing ensures the removal of impurities, aggregates, and host cell proteins from the antibody product, enhancing its efficacy and safety. As pharmaceutical and biotechnology companies focus on developing novel antibody therapeutics, efficient downstream processing becomes essential for optimizing production yields, reducing costs, and accelerating ime-to-business.
 

Antibody Production Market, By Type (2023)
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Based on type, the antibody production market is segmented into monoclonal antibodies, polyclonal antibodies, and other antibodies. The monoclonal antibodies segment accounted for 59.1% of the industry share in 2022. Monoclonal antibodies, with their exceptional specificity and versatility, are rapidly gaining prominence as pivotal components in cutting-edge medical treatments. Moreover, advancements in biomanufacturing technologies, such as cell line development, cultivation, and purification techniques, are playing a pivotal role in enhancing production efficiency and yield.
 

Based on end-use, the antibody production market is segmented into pharmaceutical & biotechnology companies, diagnostic laboratories, research institutes, and other end-users. The pharmaceutical & biotechnology companies segment is projected to witness significant expansion of 12.6% by 2032. Pharmaceutical and biotechnology firms are actively investing in optimizing antibody production processes, from cell line engineering and expression systems to purification technologies. Moreover, increasing prevalence of chronic illnesses such as diabetes, cancer, and cardiovascular disorders, along with the increasing need for therapeutic antibodies.
 

North America Antibody Production Market, 2020 – 2032 (USD Billion)
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North America antibody production market accounted for 49.1% industry share in 2022. A prominent progression driver for the industry in North America is the region's robust healthcare infrastructure and substantial investment in research and development. Moreover, the presence of advanced pharmaceutical and biotechnology industries, coupled with strong academic and research institutions, creates an environment conducive to innovation and product development. Additionally, the increasing adoption of targeted therapies and precision medicine approaches further fuels the demand for high-quality antibodies. Furthermore, North America's emphasis on technological advancements, well-established regulatory frameworks, and collaborations between industry and academia fosters a dynamic ecosystem.
 

Antibody Production Market Share

Major industry players operating in the antibody production market include :

  • Thermo Fisher Scientific, Inc.
  • GE Healthcare
  • Merck KGaA
  • Sartorius AG
  • Eppendorf AG
  • Danaher Corporation
     

Antibody Production Industry News:

  • In December 2022, Bio-Rad Laboratories, Inc. launched its pioneer antibody discovery platform. This newly antibody discovery service specifically designed to develop best-in-class biologic candidates. This strategy helped the company to expand its service offering and customer base.
     
  • In December 2022, Merck collaborated with Mersana Therapeutics, Inc. to discover novel antibody-drug conjugates (ADCs). Mersana's immunoconjugate platform is engineered to create ADCs that activate STING signaling within immune cells situated in tumors and tumor cells expressing antigens.
     

The antibody production market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD from 2018 to 2032, for the following segments:

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By Process

  • Upstream processing
  • Bioreactors
  • Consumables 
  • Downstream processing      
  • Chromatography systems
  • Chromatography resins
  • Filtration       
  • Filtration systems
  • Filtration consumables & accessories systems

By Type 

  • Monoclonal antibodies
  • Polyclonal antibodies
  • Other antibodies

By End-use

  • Pharmaceutical & biotechnology companies
  • Diagnostic laboratories
  • Research institutes
  • Other end-users

The above information is provided for the following regions and countries:

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • Japan
    • China
    • India
    • Australia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • Rest of Middle East & Africa

 

Authors: Mariam Faizullabhoy, Gauri Wani

Frequently Asked Questions (FAQ) :

Global market for antibody production accounted for USD 16.1 billion in 2023 and is estimated to grow at 11.7% CAGR through 2032, owing to the increasing adoption of targeted therapies.
The monoclonal antibodies segment accounted for 59.1% of the market share in 2022 and will continue to witness high demand backed by the exceptional specificity and versatility of monoclonal antibodies
North America market held over 49% revenue share in 2022 and is anticipated to grow at considerable rate during 2023-2032, driven by the region's robust healthcare infrastructure and substantial investment in R&D.
Thermo Fisher Scientific, Inc., GE Healthcare, Merck KGaA, Sartorius AG, Eppendorf AG, Danaher Corporation, among others.

Antibody Production Market Scope

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Premium Report Details

  • Base Year: 2023
  • Companies covered: 10
  • Tables & Figures: 359
  • Countries covered: 19
  • Pages: 220
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