Cold Plasma Market Size & Share 2023 to 2032
Market Size by Pressure (Atmospheric Pressure Cold Plasma, Low-Pressure Cold Plasma), Application (Wound Healing, Cancer Treatment, Dentistry, Blood Coagulation), End Use (Hospital, Dental Clinic, Research and Academic Institution) – Global Forecast.
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Cold Plasma Market Size
Cold Plasma Market size was valued at USD 1.8 billion in 2022 and is estimated to account for USD 6.9 billion by 2032. Cold plasma is a state of matter similar to traditional (thermal) plasma but with significantly lower temperatures. Cold plasma efficiently disinfects hospitals, sterilizing surfaces, and equipment without heat damage, reducing HAIs, complications, extended stays, and healthcare costs.
Cold Plasma Market Key Takeaways
Market Size & Growth
According to CDC report, in the U.S., hospital-acquired infections (HAIs) lead to approximately 1.7 million infections and 99,000 deaths each year. Thus, the increasing prevalence of HAIs in healthcare settings is driving the adoption of cold plasma technology.
In addition, the versatile applications of cold plasma technology, such as wound healing, surface disinfection, medical equipment sterilization, and dental care, are fueling its demand in the healthcare sector. This demand is driven by the imperative to mitigate infection risks, improve patient safety, and enhance the overall quality of healthcare services.
COVID-19 Impact
The COVID-19 pandemic disrupted the cold plasma market, resulting in supply chain disruptions, export bans, and delays in essential product deliveries. Moreover, issues included transportation bottlenecks, reduced manufacturing capacity, and a shortage of healthcare workers. However, as COVID-19 restrictions eased and healthcare services began to recover, the demand for cold plasma in disease treatment is projected to rise, leading to market growth in the subsequent period.
Cold Plasma Market Trends
Cold plasma is being explored for its potential in cancer treatment, particularly in oncology which is estimated to reach USD 690.4 billion by 2032. It is used to selectively target and kill cancer cells without harming healthy tissue. For instance, the Jerome Canady Research Institute (JCRI) and US Medical Innovations (USMI) have achieved success in an FDA Phase 1 Clinical Trial by using Canady Helios Cold Plasma (CHCP) alongside tumor resection. This approach selectively eliminates cancer cells at the surgical margin without harming healthy tissue, resulting in reduced local recurrence, improved overall survival, and the potential eradication of post-surgery residual cancer cells.
Cold Plasma Market Analysis
The market by pressure is categorized into atmospheric pressure cold plasma, and low-pressure cold plasma. The atmospheric pressure cold plasma (APCP) segment garnered USD 1.5 billion revenue size in the year 2022. The dominance of the segment can be attributed to its versatile, non-thermal, and practical nature.
Therefore, its ability to offer innovative treatment options and sustainable solutions has driven its market leadership.
Based on application, the cold plasma market is segmented into wound healing, cancer treatment, dentistry, blood coagulations, and other applications. The wound healing segment dominated the market and accounted for over 35% business share in the year 2022. High segment growth is driven by its capacity to accelerate tissue regeneration and heal wounds effectively without causing heat damage.
The cold plasma market by end-use is categorized into hospitals, dental clinics, research and academic institutions, and other end-users. The hospitals segment garnered USD 786 million revenue size in the year 2022. The segment's dominance is driven by its increased usage of infection control supplies, reducing the risk of hospital-acquired infections (HAIs), among others.
U.S. cold plasma market accounted for USD 679 million revenue size in 2022 and is predicted to witness substantial market growth over the analysis timeline.
Cold Plasma Market Share
The cold plasma industry is consolidated, with major players such as Adtec Healthcare, and few others dominating the market. These companies focus on ongoing product innovation, geographical expansion, and partnerships to secure substantial market share. For instance, in September 2023, Adtec Healthcare's Steriplas cold plasma device became the first of its kind in Taiwan, with an exclusive partnership with SG Biomedical enabling a strategic entry into the Taiwan healthcare market, projected to boost revenue of the company through this innovative medical technology catering to local needs.
Some of the eminent market participants operating in the cold plasma industry include:
Cold Plasma Industry News:
Cold plasma market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD from 2018 to 2032 for the following segments:
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By Pressure, 2018 – 2032 (USD Million)
By Application, 2018 – 2032 (USD Million)
By End-use, 2018 – 2032 (USD Million)
The above information is provided for the following regions and countries:
Research methodology, data sources & validation process
This report draws on a structured research process built around direct industry conversations, proprietary modelling, and rigorous cross-validation and not just desk research.
Our 6-step research process
1. Research design & analyst oversight
At GMI, our research methodology is built on a foundation of human expertise, rigorous validation, and complete transparency. Every insight, trend analysis, and forecast in our reports is developed by experienced analysts who understand the nuances of your market.
Our approach integrates extensive primary research through direct engagement with industry participants and experts, complemented by comprehensive secondary research from verified global sources. We apply quantified impact analysis to deliver dependable forecasts, while maintaining complete traceability from original data sources to final insights.
2. Primary research
Primary research forms the backbone of our methodology, contributing nearly 80% to overall insights. It involves direct engagement with industry participants to ensure accuracy and depth in analysis. Our structured interview program covers regional and global markets, with inputs from C-suite executives, directors, and subject matter experts. These interactions provide strategic, operational, and technical perspectives, enabling well-rounded insights and reliable market forecasts.
3. Data mining & market analysis
Data mining is a key part of our research process, contributing nearly 20% to the overall methodology. It involves analysing market structure, identifying industry trends, and assessing macroeconomic factors through revenue share analysis of major players. Relevant data is collected from both paid and unpaid sources to build a reliable database. This information is then integrated to support primary research and market sizing, with validation from key stakeholders such as distributors, manufacturers, and associations.
4. Market sizing
Our market sizing is built on a bottom-up approach, starting with company revenue data gathered directly through primary interviews, alongside production volume figures from manufacturers and installation or deployment statistics. These inputs are then pieced together across regional markets to arrive at a global estimate that stays grounded in actual industry activity.
5. Forecast model & key assumptions
Every forecast includes explicit documentation of:
✓ Key growth drivers and their assumed impact
✓ Restraining factors and mitigation scenarios
✓ Regulatory assumptions and policy change risk
✓ Technology adoption curve parameter
✓ Macroeconomic assumptions (GDP growth, inflation, currency)
✓ Competitive dynamics and market entry/exit expectations
6. Validation & quality assurance
The final stages involve human validation, where domain experts manually review filtered data to identify nuances and contextual errors that automated systems might miss. This expert review adds a critical layer of quality assurance, ensuring data aligns with research objectives and domain-specific standards.
Our triple-layer validation process ensures maximum data reliability:
✓ Statistical Validation
✓ Expert Validation
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Trust & credibility
Verified data sources
Trade publications
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Industry databases
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Regulatory filings
Government procurement records and policy documents
Academic research
University studies and specialist institution reports
Company reports
Annual reports, investor presentations, and filings
Expert interviews
C-suite, procurement leads, and technical specialists
GMI archive
13,000+ published studies across 30+ industry verticals
Trade data
Import/export volumes, HS codes, and customs records
Parameters studied & evaluated
Every data point in this report is validated through primary interviews, true bottom-up modelling, and rigorous cross-checks. Read about our research process →