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Physiological Saline Market Size - Drug Type (Normal Saline, Hypotonic), Packaging Type (Flexible Bag, Plastic Bottle), Application (Chronic Disease, Acute Health Conditions), End-user, Global Forecast 2023 – 2032

  • Report ID: GMI4322
  • Published Date: Aug 2023
  • Report Format: PDF

Physiological Saline Market Size

Physiological Saline Market size accounted for USD 5.3 billion in 2022 and is estimated to grow at 6.2% to reach USD 9.6 billion by 2032. The increasing prevalence of chronic diseases requiring intravenous therapies, such as cancer, diabetes, and cardiovascular conditions, fuels the demand for saline solutions.

Physiological Saline Market

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The aging population and a rise in surgical procedures contribute to the need for sterile saline for wound irrigation and hydration. Also, advancements in medical technology and the expanding healthcare infrastructure promote the usage of saline in various medical settings. Furthermore, the ongoing focus on patient safety and infection control drives the demand for sterile solutions like saline, in turn propelling the adoption across all geographies.

Physiological saline is a sterile solution that closely resembles the composition of bodily fluids, particularly extracellular fluid. It is composed of 0.9% sodium chloride (NaCl) dissolved in water, making it isotonic and compatible with the body's physiological conditions. Physiological saline is commonly used in medical and healthcare settings for various purposes, including intravenous fluid replacement, hydration therapy, medication administration, and wound irrigation. It serves as a source of electrolytes and helps maintain fluid balance in the body.

COVID-19 Impact

The outbreak of COVID-19 pandemic had a positive impact on the physiological saline market. The heightened demand for medical supplies, particularly for intravenous hydration and respiratory treatments, strained the global supply chain. This surge in demand led to sporadic shortages, price fluctuations, and increased production efforts to meet healthcare needs. The pandemic highlighted the importance of maintaining a stable supply of essential medical resources like saline solutions, emphasizing the need for robust supply chain strategies and production capacities to address future healthcare crises effectively. The surge in demand for saline during the pandemic may have prompted manufacturers to expand their production capabilities.

Physiological Saline Market Trends

The expanding population, high prevalence of chronic diseases, technological advancements in medicine, and improved access to healthcare services are some of the factors responsible for increased demand for medical and surgical procedures. As the prevalence of chronic diseases is continuously rising, the demand for surgical procedures and medical interventions to treat and manage such diseases is also increasing. More number of people seek medical attention, undergo diagnostic procedures, or medical interventions leading to the increasing demand for physiological saline. Surgical interventions, ranging from minor procedures to complex operations, often require the use of saline for various purposes before, during, and after surgery. It is used for purposes such as irrigation, wound cleansing, tissue manipulation, and intravenous fluid administration during the procedures. Due to its sterile, isotonic nature, and compatibility with the human body; it is highly preferred across all healthcare settings.

Physiological Saline Restraint

The cost of saline has become a significant challenge affecting physiological saline market development. The pricing of saline solutions, influenced by factors such as production costs, supply chain dynamics, and regulatory requirements, has seen an upward trend. This increase in cost poses a burden on healthcare facilities, hospitals, and patients alike. Healthcare settings, including hospitals, clinics, and other medical facilities, operate within certain budgetary limitations.

The affordability and purchasing decisions of these healthcare organizations may be influenced by the price of physiological saline. The rising cost of saline impacts the financial sustainability of healthcare systems, making it challenging for healthcare providers to allocate resources efficiently. It can lead to budget constraints, compromising the availability and accessibility of saline solutions, particularly in resource-limited settings. Healthcare providers may look for alternatives to physiological saline if the price is viewed as exorbitant or if alternative products are more affordable.

Physiological Saline Market Analysis

Physiological Saline Market Size, By Type, 2021 - 2032 (USD Billion)

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By type, the physiological saline market is classified into normal saline, hypertonic saline, and hypotonic saline. The normal saline segment accounted for a market share of 64.5% in 2022 and is expected to grow at a CAGR of 6.3% by 2032. Normal saline is a widely used type of saline as it is isotonic to human blood plasma, which prevents cells from swelling or shrinking, minimizing the risk of cellular damage. It can be used to dilute and give a variety of intravenous pharmaceuticals because it is compatible with a wide range of medications. It is a versatile solution suitable for a wide range of medical applications, including intravenous hydration, wound cleansing, and respiratory treatments. Due to the safety and effectiveness of the normal saline used for restoring fluid volume in patients with dehydration and to dilute medications that are administered intravenously, it is a preferred choice in many clinical settings, ensuring patient safety and optimal therapeutic outcomes.

By packaging type, the physiological saline market is segmented into plastic bottles, flexible bags, and glass bottles. The plastic bottles segment is expected to grow at 6.2% by 2032. Plastic is lightweight and durable, making it easier to handle, transport, and store. This results in lower shipping costs and reduced risk of breakage during transportation, ensuring the availability of intact and sterile saline products. Also, plastic packaging is less prone to shattering, which eliminates the risk of glass fragments contaminating the saline solution. This enhances patient safety and minimizes the chances of injury during handling. Owing to the advantages of plastic bottle over the other types of packaging type including, safety, compatibility, cost-effectiveness, and wide availability of plastic bottles.

Physiological Saline Market Share, By Application (2022)

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Based on application, the physiological saline market is segmented into acute health conditions, chronic diseases, skin abrasions & burns, and other applications. Acute health conditions accounted for largest industry share of 40.9% in 2022. The patients with acute health conditions usually seek care in emergency departments and critical care units, where prompt stabilization and treatment are required. Physiological saline is heavily used in these circumstances for hydration, fluid resuscitation, and drug administration.

By end-use, the physiological saline market is segmented into hospitals, ambulatory surgical centers, and other end-users. The hospitals segment is expected to grow at 6.5% up to 2032. Hospitals are the primary end-users of physiological saline solutions. Due to the extensive range of medical procedures being performed in hospitals requiring intravenous fluid therapy, the demand for the physiological saline is higher in hospitals. Hospitals often use physiological saline for purposes such as hydration, fluid resuscitation, medication administration, and electrolyte balance. The increasing number of hospital admissions, driven by population growth and the prevalence of chronic diseases, leads to a higher demand for saline solutions in hospitals.

 U.S. Physiological Saline Market Size, 2020 – 2032 (USD Billion)

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North America is the largest industry for physiological saline in which the U.S. physiological saline market was valued at USD 2.3 billion in 2022. Due to large population base, the demand for healthcare services also increases, eventually increasing the demand for physiological saline in the country. The healthcare infrastructure in the U.S. is well-developed including hospitals, clinics, and other medical facilities. Such well-established healthcare facilities provide a wide range of healthcare services, including surgical procedures, emergency care, and critical care, which utilizes the physiological saline for different purposes.

Physiological Saline Market Share

Major market players operating in the physiological saline:

  • Braun Melsungen AG,
  • Baxter International Inc
  •  Fresenius Kabi
  •  Otsuka Pharmaceutical Co.Ltd
  •  Hospira (Pfizer), and Grifols S.A.

Physiological Saline Industry News:

  • In August 2020, ICU Medical, Inc. entered into a long-term agreement with Grifols to distribute a full line of non-PVC/non-DEHP IV containers for 0.9% Sodium Chloride Injection, USP to customers in the U.S. This strategy helped the company to expand its offerings and thereby increase revenue.
  • In May 2019, B. Braun announced an investment of USD 1 billion into new and existing IV fluid manufacturing facilities across the U.S. to address the IV solution shortage. The investments include a new state-of-the-art manufacturing facility in Florida, and modernizations to existing facilities in California and Pennsylvania. This strategy helped the company to expand its manufacturing capacity and cater to rising demand in the country.

The physiological saline market research report includes an in-depth coverage of the industry with estimates & forecast in terms of revenue in USD from 2018 to 2032, for the following segments:

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By Type

  • Normal saline
  • Hypertonic saline
  • Hypotonic saline

By Packaging Type

  • Plastic bottle
  • Flexible bag
  • Glass bottle

By Application

  • Acute health conditions
  • Chronic diseases
  • Skin abrasions and burns
  • Other applications


  • Hospitals
  • Ambulatory surgical centers
  • Other end-users

The above information is provided for the following regions and countries:

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • Japan
    • China
    • India
    • Australia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East and Africa
    • South Africa
    • Saudi Arabia
    • Rest of Middle East and Africa


Authors: Mariam Faizullabhoy, Gauri Wani

Frequently Asked Questions (FAQ) :

Global market size for physiological saline was USD 5.3 billion in 2022 and will record USD 9.6 billion by end of 2032 due to the higher prevalence of chronic diseases requiring intravenous therapies, such as cancer, diabetes, and cardiovascular conditions

The plastic bottles packaging type segment is expected to observe 6.2% CAGR from 2023-2032 driven by benefits, such as lower shipping costs and reduced risk of breakage during transportation

The hospitals segment is expected to record 6.5% CAGR from 2023-2032 owing to the extensive range of medical procedures performed

U.S. physiological saline industry size was USD 2.3 billion in 2022 and is anticipated to witness considerable growth rate through 2032 owing to the surging demand for healthcare services across the country

Physiological Saline Market Scope

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Premium Report Details

  • Base Year: 2022
  • Companies covered: 10
  • Tables & Figures: 213
  • Countries covered: 19
  • Pages: 200
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