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Hemophilia Treatment Market - By Disease Type, By Product, By Patient, By Treatment Regime, By Therapy, By Route of Administration, By End Use - Global Forecast, 2026-2035
Report ID: GMI2772
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Published Date: December 2025
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Report Format: PDF
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Authors: Mariam Faizullabhoy, Gauri Wani
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Base Year: 2025
Companies covered: 14
Tables & Figures: 437
Countries covered: 19
Pages: 163
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Hemophilia Treatment Market
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Hemophilia Treatment Market Size
The global hemophilia treatment market size was valued at USD 15.2 billion in 2025. The market is expected to grow from USD 16 billion in 2026 to USD 27.2 billion in 2035, at a CAGR of 6.1% during the forecast period, according to the latest report published by Global Market Insights Inc.
The market is experiencing increasing growth, primarily escalated due to the increasing prevalence of hemophilia A and B, along with the rising adoption of prophylactic therapies, also the introduction of advanced non-factor and gene therapies. For instance, Novo Nordisk mentions that 1 in 10,000 people globally suffer from hemophilia. Also, according to World Federation of Hemophilia, more than 233,577 hemophilia cases worldwide were found, stimulating the market demand.
Hemophilia treatment refers to therapeutics that are aimed at preventing or controlling bleeding episodes caused by deficiencies in clotting factors (Factor VIII or IX). These treatments include factor replacement therapies, non-factor replacement therapies, and gene therapies that offer potential long-term solutions. These interventions help maintain hemostasis, reduce complications, and improve quality of life for patients.
Key players stimulating the growth of the market include leading biopharmaceutical and healthcare companies such as Takeda Pharmaceuticals, CSL Behring, Pfizer, Sanofi, and F. Hoffmann-La Roche, which offer a wide range of recombinant factor concentrates, extended half-life products, and innovative gene therapy solutions. These companies play critical roles in product innovation, clinical trials, regulatory approvals, and expanding global access programs, thereby stimulating the adoption and expansion of hemophilia treatments worldwide.
Between 2022 and 2024, the market witnessed considerable growth, driven by increased diagnosis rates, improved access to therapies in emerging markets, and the launch of novel non-factor therapies. For instance, the global market was valued at about USD 13.1 billion in 2022 and reached around USD 14.4 billion in 2024. This growth can be majorly attributed to the rising prevalence of hemophilia, the adoption of prophylactic regimens, and the availability of advanced recombinant and gene therapy products that reduce dependency on frequent infusions.
15% market share
Hemophilia Treatment Market Trends
Hemophilia Treatment Market Analysis
The global market was valued at USD 13.1 billion and USD 13.7 billion in 2022 and 2023, respectively. The market size reached USD 15.2 billion in 2025, growing from USD 14.4 billion in 2024.
Based on disease type, the global market is segmented into hemophilia A, hemophilia B, and other disease types. The hemophilia A segment has asserted its dominance in the market by securing a significant market share of 76.6% in 2025 and is anticipated to grow at a CAGR of 6% over the forecast years.
Based on the product, the global hemophilia treatment market is classified into recombinant factor concentrates, plasma-derived factor concentrates, extended half-life products, desmopressin, antifibrinolytic agents, gene therapy products and other products. The recombinant factor concentrates segment accounted for the highest market revenue of USD 7.1 billion in 2025 and is projected to grow at a CAGR of 6.2% during the analysis period.
Based on the patient, the global hemophilia treatment market is classified into pediatric and adult. The adult segment accounted for the highest market revenue of USD 8.8 billion in 2025 and is projected to grow at a CAGR of 6% during the analysis period.
Based on treatment regime, the global hemophilia treatment market is classified into prophylaxis and on demand. The prophylaxis segment held a market share of 72.4% in 2025 and is projected to reach by USD 19.6 billion till 2035.
Based on the therapy, the global hemophilia treatment market is classified into factor replacement therapy and non-factor replacement therapy. The factor replacement therapy segment accounted for the highest market revenue of USD 13 billion in 2025 and is projected to grow at a CAGR of 5.9% during the analysis period.
Based on the route of administration, the global hemophilia treatment market is classified into injectable, nasal spray and oral. The injectable segment accounted for the highest market revenue of USD 12.8 billion in 2025 and is projected to grow at a CAGR of 5.9% during the analysis period.
Based on end use, the global hemophilia treatment market is classified into hospitals, clinics, hemophilia treatment centers and other end users. The hospitals segment held a market share of 36.2% in 2025 and is projected to reach by USD 9.9 billion till 2035.
North America Hemophilia Treatment Market
The North America market dominated the global market with a market share of 44.2% in 2025.
The U.S. hemophilia treatment market was valued at USD 5.3 billion and USD 5.6 billion in 2022 and 2023, respectively. The market size reached USD 6.1 billion in 2025, growing from USD 5.8 billion in 2024.
Europe Hemophilia Treatment Market
Europe market accounted for USD 3.6 billion in 2025 and is anticipated to show lucrative growth over the forecast period.
Germany dominates the Europe hemophilia treatment market, showcasing strong growth potential.
Asia Pacific Hemophilia Treatment Market
The Asia Pacific market is anticipated to grow at the highest CAGR of 6.6% during the analysis timeframe.
China hemophilia treatment market is estimated to grow with a significant CAGR, in the Asia Pacific market.
Latin American Hemophilia Treatment Market
Brazil leads the Latin American market, exhibiting remarkable growth during the analysis period.
Middle East and Africa Hemophilia Treatment Market
Saudi Arabia market is expected to experience substantial growth in the Middle East and Africa market in 2025.
Hemophilia Treatment Market Share
The global market is moderately consolidated, with leading biopharmaceutical and specialty healthcare companies dominating the space, while innovation continues to thrive among emerging players. Top 5 companies such as Takeda Pharmaceutical Company Limited, CSL Behring, Novo Nordisk, Genentech (F. Hoffmann-La Roche), and Swedish Orphan Biovitrum AB (Sobi) collectively hold approximately 60% of the global market. These players are actively investing in research and development to expand their product portfolios, enhance treatment efficacy, and introduce next-generation therapies such as gene therapy and extended half-life factor products.
The market also witnesses strategic collaborations, licensing agreements, and mergers and acquisitions aimed at accelerating the commercialization of innovative therapies and expanding geographic reach. Additionally, other prominent companies including Bayer Healthcare, Biogen, Biotest AG, Ferring B.V., Kedrion, Octapharma, Pfizer, Sanofi SA, BioMarin Pharmaceutical Inc., and others contribute significantly by focusing on specialized products and advanced treatment modalities. This dynamic environment fosters rapid technological advancements, competitive differentiation, and improved patient outcomes, driving the overall growth and diversification of the market.
Hemophilia Treatment Market Companies
Prominent players operating in the hemophilia treatment industry are as mentioned below:
Takeda Pharmaceutical is a leading player in the market, holding a significant share of 15% through its comprehensive portfolio of factor replacement therapies and innovative non-factor solutions. The company offers well-established products for Factor VIII replacement, alongside Feiba, a bypassing agent for inhibitor patients. Takeda’s competitive advantage lies in its strong focus on rare diseases, global distribution network, and continuous investment in next-generation therapies, including gene therapy platforms.
CSL Behring maintains a dominant position in the market with a robust portfolio of plasma-derived and recombinant therapies. Key products which provide improved dosing convenience and clinical outcomes. The company leverages its expertise in plasma fractionation and biologics manufacturing, combined with strong global reach and strategic partnerships, to drive adoption across major markets.
Novo Nordisk is a major contributor to the market, offering a diverse range of recombinant factor therapies and novel solutions for bleeding disorders. Its flagship products include NovoSeven RT, a recombinant Factor VIIa therapy widely used for inhibitor patients, and Esperoct, an extended half-life Factor VIII product. Novo Nordisk’s competitive edge stems from its strong clinical research capabilities, global presence, and emphasis on personalized treatment approaches.
Hemophilia Treatment Industry News
The hemophilia treatment market research report includes in-depth coverage of the industry with estimates and forecast in terms of revenue in USD Million from 2022 - 2035 for the following segments:
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Market, By Disease Type
Market, By Product
Market, By Patient
Market, By Treatment Regime
Market, By Therapy
Market, By Route of Administration
Market, By End Use
The above information is provided for the following regions and countries: