Bioactive Glass Market Size - By Composition, Form, Method, Application, End Use, Property Industry Analysis, Share, Growth Forecast, 2025 - 2034

Report ID: GMI14066
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Published Date: June 2025
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Report Format: PDF

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Bioactive Glass Market Size

The global bioactive glass market reached USD 1.2 billion in 2024. The market is expected to grow from USD 1.3 billion in 2025 to USD 2.1 billion in 2034, at a CAGR of 6%.
 

Bioactive Glass Market

The biomedical field has advanced considerably due to the positive interaction of bioactive glass with biological tissues which makes it a transformative material. Unlike inactive materials, bioactive glass supports soft tissue, bones, and regenerates actively. This active regenerative capability is driven by controlled therapeutic ion release bioactive glass contains which supports osteogenesis, angiogenesis, and antimicrobial activity.
 

The bioactive glass market has expanded considerably in various clinical areas. In orthopedic, its increased usage in bone grafts, spinal fusions, and trauma repair cycles is noticed due to bioactive glass’s stimulation for bone growth and integration. Dentistry is another important bioactive glass application domain where fillings, periodontal treatment, and implants outcomes are enhanced by bioactive glass. It also has expanding role in regenerative medicine scaffolds and drug delivery systems for tissue engineering.
 

The development of newer processing methods like porosity, degradation rate, ion release customization, sol-gel synthesis, melt derived techniques, and additive manufacturing enables the creation of more tailored and high-performance bioactive glass formulations. These innovations widen the applicability scope of bioactive glass in the medical field as they enable customization in porosity, rate of degradation, and ion release.
 

Geographically, developed nations such as Europe and North America are at the forefront of adoption owing to their robust research ecosystems, sophisticated healthcare infrastructure, and spending on healthcare technologies. Phosphate and borate-based variants alongside traditional 45S5 bioglass serve the specific clinical requirement interactions and biologically offer a growing phase compositional range to suit evolving clinical needs.
 

In comparison, the Asia Pacific region is rapidly emerging as a core market due to the rising spending on healthcare and increasing access to advanced medical technologies. All in all, the demand for materials integrated and actively participating with the biological system is on the rise along with clinically tested bioactive materials and medical solutions result in an expanding market for bioactive glass. Its sustained innovation and multidisciplinary applications spanning the globe position the market for ongoing growth.
 

Bioactive Glass Market Trends

Integration of Bioactive Glass in Advanced Drug Delivery Systems: The use of bioactive glass is growing in targeted drug delivery systems due to its capability of ionotropic therapy. Its cystic structure enables it to pick up and release antibiotics, anti-inflammatory drugs, and even growth factors augmenting healing locally while at the same time reducing elimination of these agents from the body to other areas. This is particularly important in surgical orthopaedics and dentistry where there is need to control infections within the surgical field and at the same time encourage bony repair. The unique characteristics of bioactivity and bioactive glass’s ability to release drugs strategically makes it to be regarded as a biomaterial of two functions, turning it into a new scope across regenerative medicine and treatment of chronic diseases.
 

Growing Adoption of Additive Manufacturing (3D Printing) Techniques: The incorporation of 3D printing technology yields scaffolds with enhanced tissue integration shear strengthening acceleration of healing outcomes. The advancement 3D printing technology facilitates the employment of novel compositions of bioactive glass in complex geometries for bone and tissue engineering.
 

Expansion into Cosmetic and Personal Care Products: Bioactive glass inclusion into dental and skincare products is on the rise due to its microbial, anti-microbial, antimicrobial, and remineralizing properties. And in skincare products, it helps rebuild dermal tissues and aids with wound healing. Biocompatible, non-toxic, and effective materials are preferred by consumers today which is propelling the expansion. As education increases alongside formulation sophistication, cosmetic brands are bioactive glass to develop premium products, leveraging the material’s functional benefits, and marking a substantial shift diversifying the material’s end-use portfolio.
 

Bioactive Glass Market Analysis

Bioactive Glass Market Size, By Composition, 2021-2034 (USD Billion)

On the basis of composition, the market is segmented into 45S5 Bioglass, S53P4 (BonAlive), 13-93, 58S, 70S30C, phosphate-based, borate-based, and other compositions. 45S5 bioglass holds a significant share at a valuation of USD 545.4 million in 2024.
 

  • Applying the 45S5 Bioglass technology in the industrial field leads to the production of the most known and utilized bioactive glass. They are well known for their bioactive features and their capability of bonding aggressively to bone tissue. Its composition includes 45% of silica, 24.5% calcium oxide, 24.5% sodium oxide and 6% of phosphorus pentoxide.
     
  • Due to its ability to hasten the development of hydroxycarbonate apatite which aids in bone tissue formation, it is widely used in orthopaedic treatments and in dental medicine. This composition facilitates Osteoconductivity and possesses antibacterial properties. The solid clinical performance provided with the large scale available of the 45S5 helps maintain its market leader position in bone grafts, scaffolds and dental implants due to the high and growing world demand.
     

Bioactive glass market from S53P4 (BonAlive) segment was priced at USD 387.1 million in 2024 and is expected to reckon USD 728.1 million in 2034.
 

  • Commercially known as BonAlive, S53P4 is a bioactive glass composition well known for its high osteoporosis and osteostimulative properties. It contains approximately 53% of silicate, 23% sodium oxide, 20% calcium oxide and 4% of pentoxide of phosphorus. Assisting bone formation while preexisting bacterial infection hampers growth makes this formulation effective in treatment of bone infections and chronic osteomyelitis.
     
  • BonAlive is widely used in orthopedic surgeries and bone regeneration therapies, especially where infection risk is high. The emerging markets of Europe and North America have facilitated the adoption of these bioactive glasses as a bone substitute and antimicrobial agents, thus supporting the bioactive glass segment’s expansion.

 

Bioactive Glass Market Revenue Share, By Form, (2024)

On the basis of form, the market is segmented into powder, granules & particles, scaffolds & porous structures, coatings, fibres & meshes, composites, and other. Powder holds the market share of 39.8% in 2024 and is expected to grow at a 6.4% of CAGR during the forecast period.
 

  • The bioactive glass market captures different forms tailored for biomedical purposes. The most common form is the powder which is frequently used in bone grafting and dental procedures due to simple mixing with other biomaterials. Granules and particles are often employed to enhance bone void fillers and scaffolds and provide fast-acting bone bonding due to increased surface area.
     
  • Fibers and meshes are made for lightweight and flexible uses in soft tissue repair and wound care. Composites are aimed at bioactive glass strengthened with polymers or ceramics, to enhance bioactivity and mechanical strength in bearable implants. Scaffolds and porous structures are essential parts in tissue engineering since they provide a 3D design on which cells can grow and vascularize. Coatings of bioactive glass serve to improve the osteointegration of metal implants and their microbial-load impact, thus, increasing their integration and lifespan. Other forms are specialized shapes and custom-made constructs developed through advanced fabrication techniques like 3D printing, broadening the application of bioactive glass in regenerative medicine.
     

On the basis of method, the market is segmented into melt derived, sol-gol, flame spray synthesis, microwave processing, 3D printing and others. Melt derived estimated to grasp a value of USD 729.4 million in 2025 and is expected to grow at a 6.2% of CAGR during the forecast period.
 

  • The bioactive glass market has a high competition due to varying processing techniques which alter the material's properties and uses. For example, ‘melt bioactive glass’ is manufactured by ‘melting’ the stone’s raw materials. Weighing more than classical biomedicine glass, which epitomizes reliability in its structure and make, ‘melt derived bioactive glass’ is homogeneous and dense. Ideal for advanced tissue engineering, porous glasses with unmatched purity, enhanced bioactivity and surface area can be obtained through lower-temperature chemically synthesizing sol-gel processing. Enhanced surface reactivity and coating applications can be achieved through flame spray synthesis, a scalable technique which leads to the formation of nano-sized glass powders.
     
  • Similar to flame spray synthesis, ‘microwave processing’ aids in the creation of glass with more uniform quality, enabling energy efficient glass refinement, and shortening production time. This in turn, supports ‘sustainable’ manufacturing. The invention of ‘3D printing’ allows the construction of scaffolds that are tailor-made to an individual patient’s delicate operation, augmenting personalized medicine. Other techniques such chemical vapor deposition continue to modify the properties of bioactive glass to further expand its capabilities in medicine. Collectively, these processes provide solutions specifically targeted to orthopaedics, dentistry, and tissue engineering markets.
     

On the basis of application, the market is segmented into orthopaedics, dentistry, tissue engineering & regenerative medicine, wound healing, cosmetics & personal care, and other. Orthopaedics estimated to grab a value of USD 433.9 million in 2025 and is expected to grow at a 7.1% of CAGR during the forecast period.
 

  • The bioactive glass market serves immerse applications across multiple fields. In Orthopedy, bioactive glass is used for bone grafts and spinal fusions, trauma repairs, and bone void fillers, and it enables bone healing. Dentistry employs bioactive glass for dental fillings and implants, periodontal surgeries, and endodontic materials due to its integration enhancing tissue and a reduction in infection. The tissue engineering & regenerative medicine utilize bioactive glass to manufacture scaffolds for bone and soft tissues, bone regeneration, and drug delivery systems, alongside other applied therapeutics. 
     
  • In wound healing, bioactive glass enhances tissue repair processes by inducing cell proliferation while offering antimicrobial actions. Biocompatibility and bioactivity of bioactive glass make it advantageous for skin health, and so cosmetics & personal care employ it for skin rejuvenation and repair. Lastly, other applications involve coatings for medical devices and composite biomaterials as well as veterinary use, signifying the material’s versatility. Innovation in other segments is supporting the growing global demand for biomedical and healthcare services along with driving market growth.
     

On the basis of enduse, the market is segmented into hospitals & clinics, dental clinics, ambulatory surgical centres, research & academic institutions, medical device manufacturers, pharmaceutical & biotechnology companies, and other. Hospitals and clinics estimated to grab a value of USD 485.8 million in 2025 and is expected to grow at a 6.3% of CAGR during the forecast period.
 

  • The bioactive glass market serves a variety of end users across the healthcare and research industries. Clinics and hospitals serve as the primary consumers owing to the availability of orthopaedic surgeries, dentistry, and wound care procedures that utilize bioactive glass-based products owing to tissue healing and regeneration. Dental clinics actively make use of bioactive glass materials in Restorative Dentistry for dental filling, dental implants, and periodontal surgeries improving patient’s health with minimalistic biological impacts. Bioactive glass products aid in performing fast recovery and antimicrobial property endowed minimally invasive surgeries at ambulatory surgical centres (ASCs).
     
  • Advanced biomedical research and education are spearheaded by innovation institutes whose research bioactive glasses in formulating novel designs and uses of bioactive glass, engineering new techniques within tissue engineering and regenerative medicine. Composite bioactive glass is being incorporated in devices used for bone and teeth implants to enhance the durability and adhesion as bioactive coatings of glass composites; bioactive glass is used in Medical devices. Focused therapies using bioactive glass as carrier of active principles are studied by pharmaceutical and biotechnology companies. Veterinary medicine and specialized areas of biomedicine mark the other end users demonstrating increased versatility of the material across diverse fields.
     

On the basis of property, the bioactive glass market is segmented into osteoconductivity, antimicrobial activity, angiogenic properties, biodegradability, and others. Osteoconductivity holds the market share of 50.1% in 2024 and is expected to grow at a 5.8% of CAGR during the forecast period.
 

  • The bioactive glass has important properties that increase its use in medicine. Bioactive glass allows for new bone formation and is osteoconductive. It has antimicrobial properties and therefore prevents infection at the implantation site and is useful for dental and orthopedic surgery. Bioactive glass also helps new blood vessels grow which is very useful for tissue regeneration. It also has a positive beneficial effect on tissue which adds to the range of orthopedic uses. Lastly it demonstrates phenomena when bones are grown which makes bioactive glass very helpful in regenerative medicine.

 

U.S. Bioactive Glass Market Size, 2021-2034 (USD Million)

The bioactive glass market is dominated by U.S, which accounted for a revenue of USD 358.9 million of total revenue in 2024.
 

  • The U.S. market is witnessing significant growth owing to the increasing demand in the medical and dental fields, especially in bone regeneration and orthodontic implant coating procedures. Bioactive glasses are indispensable in orthopaedics, dentistry, as well as in wound healing, owing to their impressive compatibility, bone tissue integration capability, and antibacterial action. The rise in case of osteoporosis, bone fractures, and dental abnormalities is boosting the market growth. Moreover, innovative customized and composite bioactive glasses are widening their use by improving technological performance.
     
  • Furthermore, increased awareness of patients and medical professionals relative to the effectiveness of less invasive strategies aid in the expansion. Although high marketing costs and policy issues may impede growth. All in all, the market is expecting consistent development due to the strong clinical advantages and the improvement of healthcare systems within the U.S.
     

Bioactive Glass Market Share

Key players covering a significant portion of the global bioactive glass industry include SCHOTT AG, Mo-Sci Corporation, NovaBone Products, LLC, and Stryker Corporation (and its subsidiary Ortho Vita, Inc), and DePuy Synthes from Johnson & Johnson. These companies maintain their global leadership position through comprehensive product catalogues, sophisticated manufacturing technologies, and well-established distribution systems that span multiple regions. Their strong presence across the medical, dental, and orthopedic arms ensures reliable and stable supply chains that help the companies serve a myriad of clinical uses and shifting patient demands.
 

These foremost companies optimize proprietary technologies along with other advanced bioactive glasses developed for bone regeneration, implant coating, and wound healing. The companies’ dedication to quality assurance and compliance with rigorous international benchmarks reinforce their reputation, nurturing strong relationships with healthcare services worldwide. Such policy enables the companies to serve the market with consistent, dependable, high-quality products that fulfil additional therapeutic needs.
 

Furthermore, these companies withstand market pricing fluctuations, regulatory pathways, or evolving demands in the healthcare industry due to the integrative structure of their operations. Such strategic approaches allow the companies to lead the global market while expanding and setting bioactive industry standards, thus reinforcing their predominance in bioactive glass. Continuous innovation and comprehensive service capabilities put these companies in a position to retain an upper hand in this rapidly evolving and high-opportunity market.
 

Bioactive Glass Market Companies

SCHOTT AG: SCHOTT AG is skilled in producing bioactive glass in medicine including implants and bone regeneration that SCHOTT calls their own. By employing advanced glass technology along with R&D, SCHOTT is able to produce biocompatible materials SCHOTT calls advanced and deliver biocompatible materials with excellent bonding properties. The company is able to manufacture and distribute products globally making diverse medical applications possible which guarantees accuracy, consistency and compliance with regulations. SCHOTT is an industry leader in clinical outcome innovations focusing on orthopaedics bioactive glass alongside dental bioactive glass imprints further strengthening SCHOTT's position as an industry leader.
 

Mo-Sci Corporation: Mo-Sci Corporation is known to focus on glass-based bioactive products for bone regeneration and implant coating. Also known for their glass microspheres and particulate products, the corporation centres quality alongside biocompatibility. Medical and dental grade applications are supported by climbing advanced manufacturing capabilities allowing for greater customization. Strong global partnerships as cited by many market experts makes Mo-Sci a cutting-edge supplier of bioactive glass in regenerative healthcare fields.
 

NovaBone Products, LLC: Bone graft substitutes containing bioactive glass known to accelerate the healing process are the industry offerings from NovaBone Products. The bone substitutes are combined with patented formulations that add to their value further supporting orthopedic alongside dental surgery. Efforts towards less invasive treatments further improves the company's goals shrinking the window for bioactive glasses and exposing them to tissue regeneration market while solidifying the company's strategy for expanding exposure.
 

Stryker Corporation (including Orthovita, Inc.): Stryker Corporation, along with Orthovita, Inc., offers products using innovative bioactive glasses for orthopedic and spinal uses. They have in their portfolio bone graft substitutes and coatings that enhance the healing of bones. Stryker combines innovative technology with surgical devices and delivers worldwide regenerative solutions. Strong clinical and regulatory support make patient-focused product innovation leading in the market.
 

DePuy Synthes (Johnson & Johnson): DePuy Synthes within Johnson and Johnson develops Bioactive glasses that improve the healing of bones and the acceptance of implants. Through the vast network of J&J, their innovative graft materials and surgical products are tamper free and dependable. Strict regulations and quality control policies strengthen their position in the market. Advancing orthopaedics and dental care, DePuy Synthes harness cutting-edge bioactive glass technologies to improve patient outcomes.
 

Bioactive Glass Industry News

  • In October 2023, BonAlive Biomaterials has launched bioactive glass granules targeted for the chronic wound care market. This product enhances BonAlive's position in the bioactive glass market as an innovator, considering the increasing need for orthopaedic and dental bone repair services.
     
  • In September 2023, Corning Inc. has increased its bioactive glass product portfolio by a new factory in India. This move is expected to strengthen Corning’s stance in the global market by fulfilling the demand for biocompatible materials.
     
  • In 2023, SCHOTT AG has developed a new advanced composition of bioactive glass with an intention to enhance spinal surgery outcomes. This underscores SCHOTT’s devotion to improving patient outcomes in the medical industry.
     
  • In 2023, NovaBone Products has developed new bioactive putties designed for orthopaedic usages which expands the company's product portfolio. According to the company, these products will support better patient outcomes and ease of use in advanced orthopaedic care.
     

The bioactive glass market research report includes an in-depth coverage of the industry with estimates and forecast in terms of revenue in (USD Million) & Volume in (Kilo Tons) from 2021 – 2034 for the following segments:

Market, By Composition

  • 45S5 bioglass
  • S53P4 (bonAlive)
  • 13-93 bioactive glass
  • 58S bioactive glass
  • 70S30C bioactive glass
  • Phosphate-based bioactive glass
  • Borate-based bioactive glass
  • Other compositions

Market, By Form

  • Powder
  • Granules & particles
  • Scaffolds & porous structures
  • Coatings
  • Fibers & meshes
  • Composites
  • Other forms

Market, By Method

  • Melt-derived
  • Sol-gel
  • Flame spray synthesis
  • Microwave processing
  • 3d printing/additive manufacturing
  • Other processing methods

Market, By Application

  • Orthopedics
    • Bone grafts & substitutes
    • Bone void fillers
    • Spinal fusion
    • Trauma repair
    • Other orthopedic applications 
  • Dentistry
    • Dental fillings
    • Dental implants
    • Periodontal treatment
    • Endodontic materials
    • Other dental applications
  • Tissue engineering & regenerative medicine
    • Bone tissue engineering
    • Soft tissue engineering
    • Drug delivery systems
    • Other tissue engineering applications
  • Wound healing
  • Cosmetics & personal care
  • Other applications

Market, By End Use

  • Hospitals & clinics
  • Dental clinics
  • Ambulatory surgical centers
  • Research & academic institutions
  • Medical device manufacturers
  • Pharmaceutical & biotechnology companies
  • Other end use

Market, By Property

  • Osteoconductivity
  • Antimicrobial activity
  • Angiogenic properties
  • Biodegradability
  • Other properties

The above information is provided for the following regions and countries:

  • North America 
    • U.S.
    • Canada 
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Rest of Europe 
  • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • Rest of Asia Pacific 
  • Latin America
    • Brazil
    • Mexico
    • Argentina
    • Rest Of Latin America 
  • Middle East and Africa
    • Saudi Arabia
    • South Africa
    • UAE
    • Rest of MEA

 

Authors: Kiran Pulidindi, Kunal Ahuja
Frequently Asked Question(FAQ) :
How big is the bioactive glass market?
The market size for bioactive glass was valued at USD 1.2 billion in 2024 and is projected to reach approximately USD 2.1 billion by 2034, growing at a CAGR of 6% during the forecast period.
What is the estimated value of the hospitals and clinics segment in the bioactive glass industry for 2025?
How did the U.S. perform in the bioactive glass market in 2024?
Who are the key players in the bioactive glass industry?
Bioactive Glass Market Scope
  • Bioactive Glass Market Size
  • Bioactive Glass Market Trends
  • Bioactive Glass Market Analysis
  • Bioactive Glass Market Share
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    Base Year: 2024

    Companies covered: 29

    Tables & Figures: 210

    Countries covered: 22

    Pages: 263

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