Ammonium acetate market is poised to register a significant growth rate over 2022-2028, given the strong application scope of the product as a functional additive in processed food & beverages. Ammonium acetate refers to an ammonium salt, derived through the reaction of ammonia and acetic acid. Appearing as a white-colored crystalline solid, the product is used extensively in pharmaceuticals, food preservation, and chemical analysis, among other applications.
The rapid development of novel formulations for drugs like insulin is one of the key factors driving ammonium acetate industry growth over 2022-2028. For instance, in July 2021, the U.S. FDA announced approval for the first biosimilar, interchangeable insulin product, designed to improve glycemic control in pediatric and adult patients diagnosed with Type 1 diabetes mellitus, as well as adult patients with Type 2 diabetes mellitus. Development such as these could amplify demand for pharmaceutical grade ammonium acetate, which is used in the production of drugs like insulin and penicillin, as well as in chromatography. However, certain problems associated with ammonium acetate buffers in labs, such as increased HPLC-MS backpressures upon starting of instruments following overnight storage, as well as MS sensitivity-related complexities, could restrict industry growth to a certain extent.
Food is set to emerge as a prominent end-use segment for the ammonium acetate market over the estimated timeline. This is driven mainly by the vast application scope of ammonium acetate in the food industry. Ammonium acetate can be used for various purposes, including as an acidity regulator in food additives, as a nutritional supplement or calcium intensifier, as an anti-caking agent in flour, or as a pH regulator and buffer.
Regionally, the North American ammonium acetate industry is expected to gain substantial momentum by 2028, on account of the escalating usage of the product as a de-icing solution in countries with extremely cold climates. De-icing agents like road salt are conventionally used to prevent snow and ice deposits on roads during winter. However, these products can be detrimental to environmental health, thereby prompting the usage of more biodegradable options like ammonium acetate as the preferred de-icing agents in regions like Canada.
The global ammonium acetate market is comprised of players like NASi, Tianmen Chutian Fine Chemical Co., Ltd, Wuxi Yangshan Biochemical Co., Ltd., Niacet (Kerry Group), Jarchem, Langfang Tianke Biotechnology Co., Ltd, Anhui Hongyang Chemical Co., Ltd, Shijiazhuang Runhong Technology Co., Ltd, Victor Chemical, Shandong Zhonghe Hengyuan Chemical Co., Ltd, and Jiangsu Jiatai Chemical Co., Ltd. Partnerships, collaborations, and expansions are among the key initiatives being undertaken by these entities to boost their presence in the global market.
The onset of the novel coronavirus pandemic and the unprecedented health issues it triggered has spurred the advancement of new drug discovery projects as well as clinical studies, especially pertaining to antivirals. For instance, remdesivir, a phosphoramidate prodrug that has been intracellularly converted into active triphosphate form has gained approval from the U.S. FDA as a COVID-19 treatment. In order to test the in vitro efficacy of such drugs against the novel coronavirus, various studies are being conducted, which could boost demand for products like ammonium acetate. For instance, in order to identify a starting point for a method to be potentially applied to pharmacokinetic analyses, in vitro cell assays, and dosing studies, hybrid silica surfaces along with mixed-mode chromatography with ammonium acetate mobile phase was leveraged.